Detalhe da pesquisa
1.
Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.
Immunity
; 56(2): 406-419.e7, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36792574
2.
Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.
Immunity
; 55(9): 1680-1692.e8, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35977542
3.
A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
PLoS Pathog
; 18(3): e1010409, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35344575
4.
Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
PLoS Pathog
; 16(3): e1008373, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32150583
5.
The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is pure and stable.
J Biol Chem
; 295(2): 403-414, 2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31792057
6.
Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein.
Malar J
; 19(1): 113, 2020 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32183833
7.
Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein.
Proc Natl Acad Sci U S A
; 114(48): E10438-E10445, 2017 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29138320
8.
Expression and purification optimization of an N-terminal Pfs230 transmission-blocking vaccine candidate.
Protein Expr Purif
; 160: 56-65, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30978392
9.
Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages.
Malar J
; 18(1): 426, 2019 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31849326
10.
Disulfide bond mapping of Pfs25, a recombinant malaria transmission blocking vaccine candidate.
Anal Biochem
; 542: 20-23, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29162427
11.
Assessment of Pfs25 expressed from multiple soluble expression platforms for use as transmission-blocking vaccine candidates.
Malar J
; 15(1): 405, 2016 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27515826
12.
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.
Proc Natl Acad Sci U S A
; 110(11): 4351-6, 2013 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23426631
13.
A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies.
PLoS Pathog
; 9(9): e1003618, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24068931
14.
Identification of a suppressor mutation that improves the yields of hexon-modified adenovirus vectors.
J Virol
; 87(17): 9661-71, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23824800
15.
Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes.
J Virol
; 87(10): 5372-83, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23468492
16.
Establishing RTS,S/AS01 as a benchmark for comparison to next-generation malaria vaccines in a mouse model.
NPJ Vaccines
; 9(1): 29, 2024 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38341502
17.
Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross stage recognition of glutamate-rich repeats.
bioRxiv
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961136
18.
A candidate antibody drug for prevention of malaria.
Nat Med
; 30(1): 117-129, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38167935
19.
Pfs230 Domain 7 is targeted by a potent malaria transmission-blocking monoclonal antibody.
NPJ Vaccines
; 8(1): 186, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38086855
20.
Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun
; 14(1): 4546, 2023 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37507365