Detalhe da pesquisa
1.
Bioorthogonal chemical labeling of endogenous neurotransmitter receptors in living mouse brains.
Proc Natl Acad Sci U S A
; 121(6): e2313887121, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38294939
2.
Crystal structure reveals the binding mode and selectivity of a photoswitchable ligand for the adenosine A2A receptor.
Biochem Biophys Res Commun
; 695: 149393, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38171234
3.
Tethering-based chemogenetic approaches for the modulation of protein function in live cells.
Chem Soc Rev
; 50(14): 7909-7923, 2021 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34114579
4.
Hijacking endogenous mRNA for genetic code expansion.
Nat Chem Biol
; 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38454074
5.
A conditional proteomics approach to identify proteins involved in zinc homeostasis.
Nat Methods
; 13(11): 931-937, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27617391
6.
Intracellular thermometry with fluorescent sensors for thermal biology.
Pflugers Arch
; 470(5): 717-731, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29397424
7.
Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry.
Nat Chem Biol
; 12(10): 822-30, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27526031
8.
DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels.
Angew Chem Int Ed Engl
; 57(10): 2586-2591, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29341462
9.
Affinity-Guided Oxime Chemistry for Selective Protein Acylation in Live Tissue Systems.
J Am Chem Soc
; 139(40): 14181-14191, 2017 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28915034
10.
TRP channels in oxygen physiology: distinctive functional properties and roles of TRPA1 in O2 sensing.
Proc Jpn Acad Ser B Phys Biol Sci
; 93(7): 464-482, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28769017
11.
Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds.
Mol Pharmacol
; 89(3): 348-63, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26733543
12.
A Set of Organelle-Localizable Reactive Molecules for Mitochondrial Chemical Proteomics in Living Cells and Brain Tissues.
J Am Chem Soc
; 138(24): 7592-602, 2016 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27228550
13.
Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy.
EMBO J
; 31(18): 3730-44, 2012 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22892567
14.
Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells.
Nat Methods
; 10(12): 1232-8, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24122038
15.
Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.
Amino Acids
; 48(4): 1045-1058, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26724922
16.
Compromised maturation of GABAergic inhibition underlies abnormal network activity in the hippocampus of epileptic Ca2+ channel mutant mice, tottering.
Pflugers Arch
; 467(4): 737-52, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24947601
17.
Transnitrosylation directs TRPA1 selectivity in N-nitrosamine activators.
Mol Pharmacol
; 85(1): 175-85, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24202912
18.
Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.
J Physiol
; 591(11): 2851-66, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23529130
19.
Validating subcellular thermal changes revealed by fluorescent thermosensors.
Nat Methods
; 12(9): 801-2, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26317233
20.
TRPA1 underlies a sensing mechanism for O2.
Nat Chem Biol
; 7(10): 701-11, 2011 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21873995