Detalhe da pesquisa
1.
Long-term administration of intravenous Trappsol® Cyclo™ (HP-ß-CD) results in clinical benefits and stabilization or slowing of disease progression in patients with Niemann-Pick disease type C1: Results of an international 48-week Phase I/II trial.
Mol Genet Metab Rep
; 36: 100988, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37670901
2.
Interim results from an ongoing, open-label, single-arm trial of odevixibat in progressive familial intrahepatic cholestasis.
JHEP Rep
; 5(8): 100782, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37456676
3.
Development of the Patient- and Observer-Reported PRUCISION Instruments to Assess Pruritus and Sleep Disturbance in Pediatric Patients with Cholestatic Liver Diseases.
Adv Ther
; 39(11): 5126-5143, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36066744
4.
Validation of the PRUCISION Instruments in Pediatric Patients with Progressive Familial Intrahepatic Cholestasis.
Adv Ther
; 39(11): 5105-5125, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36066745
5.
Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial.
Lancet Gastroenterol Hepatol
; 7(9): 830-842, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35780807
6.
Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function.
J Lipid Res
; 52(2): 361-73, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21068008
7.
Pharmacokinetics and pharmacodynamics of vildagliptin in healthy Chinese volunteers.
J Clin Pharmacol
; 49(1): 39-49, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18832295
8.
Efficacy and Safety of ITCA 650, a Novel Drug-Device GLP-1 Receptor Agonist, in Type 2 Diabetes Uncontrolled With Oral Antidiabetes Drugs: The FREEDOM-1 Trial.
Diabetes Care
; 41(2): 333-340, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29242349
9.
Clinical Impact of ITCA 650, a Novel Drug-Device GLP-1 Receptor Agonist, in Uncontrolled Type 2 Diabetes and Very High Baseline HbA1c: The FREEDOM-1 HBL (High Baseline) Study.
Diabetes Care
; 41(3): 613-619, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29301824
10.
Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis.
Diabetes
; 55(4): 1051-6, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16567528
11.
Effects of short-term caloric restriction on circulating free IGF-I, acid-labile subunit, IGF-binding proteins (IGFBPs)-1-4, and IGFBPs-1-3 protease activity in obese subjects.
Eur J Endocrinol
; 155(4): 575-81, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16990657
12.
Quantification of the Contribution of GLP-1 to Mediating Insulinotropic Effects of DPP-4 Inhibition With Vildagliptin in Healthy Subjects and Patients With Type 2 Diabetes Using Exendin [9-39] as a GLP-1 Receptor Antagonist.
Diabetes
; 65(8): 2440-7, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27207543
13.
Do oscillations of insulin secretion occur in the absence of cytoplasmic Ca2+ oscillations in beta-cells?
Diabetes
; 51 Suppl 1: S177-82, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11815478
14.
The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects.
Diabetes
; 52(2): 380-6, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12540611
15.
Pulsatile insulin secretion by human pancreatic islets.
J Clin Endocrinol Metab
; 87(1): 213-21, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11788649
16.
Skeletal muscle mitochondrial capacity and insulin resistance in type 2 diabetes.
J Clin Endocrinol Metab
; 96(4): 1160-8, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21307136