Detalhe da pesquisa
1.
Artificial Intelligence-Enabled Assessment of the Heart Rate Corrected QT Interval Using a Mobile Electrocardiogram Device.
Circulation
; 143(13): 1274-1286, 2021 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33517677
2.
Comparison of electrocardiograms (ECG) waveforms and centralized ECG measurements between a simple 6-lead mobile ECG device and a standard 12-lead ECG.
Ann Noninvasive Electrocardiol
; 26(6): e12872, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34288227
3.
Potential strategy for assessing QT/QTc interval for drugs that produce rapid changes in heart rate: Electrocardiographic assessment of the effects of intravenous remimazolam on cardiac repolarization.
Br J Clin Pharmacol
; 86(8): 1600-1609, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144789
4.
Long-term electrocardiographic safety monitoring in clinical drug development: A report from the Cardiac Safety Research Consortium.
Am Heart J
; 187: 156-169, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28454799
5.
Prevention of sudden cardiac death in the young: Developing a rational, reliable, and sustainable national health care resource. A report from the Cardiac Safety Research Consortium.
Am Heart J
; 190: 123-131, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28760206
6.
Moxifloxacin-induced QTc interval prolongations in healthy male Japanese and Caucasian volunteers: a direct comparison in a thorough QT study.
Br J Clin Pharmacol
; 80(3): 446-59, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26011050
7.
Validation of a Handheld 6-Lead Device for QT Interval Monitoring in Resource-Limited Settings.
JAMA Netw Open
; 7(6): e2415576, 2024 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38848063
8.
The evaluation and management of drug effects on cardiac conduction (PR and QRS intervals) in clinical development.
Am Heart J
; 165(4): 489-500, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23537964
9.
Ventricular Arrhythmias Associated With Over-the-Counter and Recreational Opioids.
J Am Coll Cardiol
; 81(23): 2258-2268, 2023 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37286256
10.
Improving the in Vivo QTc assay: The value of implementing best practices to support an integrated nonclinical-clinical QTc risk assessment and TQT substitute.
J Pharmacol Toxicol Methods
; 121: 107265, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36997076
11.
Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As.
J Pharmacol Toxicol Methods
; 123: 107270, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37164235
12.
False Negative ECG Device Results May Increase the Risk of Adverse Events in Clinical Oncology Trials.
Ther Innov Regul Sci
; 56(4): 667-676, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35471562
13.
A Randomized Thorough QT Study of Apomorphine Sublingual Film in Patients With Parkinson's Disease.
Clin Pharmacol Drug Dev
; 11(9): 1068-1077, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35899977
14.
Thorough QT/QTc Evaluation of the Cardiac Safety of Enarodustat (JTZ-951), an Oral Erythropoiesis-Stimulating Agent, in Healthy Adults.
Clin Pharmacol Drug Dev
; 10(8): 884-898, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34159762
15.
Intracellular uptake of agents that block the hERG channel can confound the assessment of QT interval prolongation and arrhythmic risk.
Heart Rhythm
; 18(12): 2177-2186, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34481984
16.
Evaluation of Cardiac Repolarization in the Randomized Phase 2 Study of Intermediate- or High-Risk Smoldering Multiple Myeloma Patients Treated with Daratumumab Monotherapy.
Adv Ther
; 38(2): 1328-1341, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33474705
17.
Evaluation of ventricular arrhythmias in early clinical pharmacology trials and potential consequences for later development.
Am Heart J
; 159(5): 716-29, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20435178
18.
ICH E14 Q&A(R2) document: commentary on the further updated recommendations on thorough QT studies.
Br J Clin Pharmacol
; 79(3): 456-64, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25060671
19.
Evaluation of the Effect of SPN-812 (Viloxazine Extended-Release) on QTc Interval in Healthy Adults.
J Clin Psychiatry
; 81(6)2020 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33049804
20.
Replacing the thorough QT study: reflections of a baby in the bath water.
Br J Clin Pharmacol
; 78(2): 195-201, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24286381