Detalhe da pesquisa
1.
Impact of neonatal NOS-1 inhibitor exposure on neurobehavioural measures and prefrontal-temporolimbic integration in the rat nucleus accumbens.
Int J Neuropsychopharmacol
; 17(2): 275-87, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24025168
2.
In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease.
J Pharmacol Exp Ther
; 334(3): 875-86, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20504913
3.
eIF2B activator prevents neurological defects caused by a chronic integrated stress response.
Elife
; 82019 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30624206
4.
Preclinical abuse liability assessment of ABT-126, an agonist at the α7 nicotinic acetylcholine receptor (nAChR).
Pharmacol Biochem Behav
; 158: 22-31, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28579351
5.
Effect of dopamine D3 antagonists on PPI in DBA/2J mice or PPI deficit induced by neonatal ventral hippocampal lesions in rats.
Neuropsychopharmacology
; 31(7): 1382-92, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16395300
6.
Synthesis and structure-activity relationships of 3,8-diazabicyclo[4.2.0]octane ligands, potent nicotinic acetylcholine receptor agonists.
J Med Chem
; 49(26): 7843-53, 2006 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17181167
7.
Loss of functional neuronal nicotinic receptors in dorsal root ganglion neurons in a rat model of neuropathic pain.
Neurosci Lett
; 376(1): 29-34, 2005 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15694269
8.
Nicotinic modulation of auditory evoked potential electroencephalography in a rodent neurodevelopmental model of schizophrenia.
Biochem Pharmacol
; 97(4): 482-487, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26032639
9.
Peripheral and central sites of action for A-85380 in the spinal nerve ligation model of neuropathic pain.
Pain
; 103(3): 269-276, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12791433
10.
5,6,7-trisubstituted 4-aminopyrido[2,3-d]pyrimidines as novel inhibitors of adenosine kinase.
J Med Chem
; 46(24): 5249-57, 2003 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-14613327
11.
Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia.
Psychopharmacology (Berl)
; 176(3-4): 312-9, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15179541
12.
Effects of α7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis.
Psychopharmacology (Berl)
; 220(4): 823-33, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22038534
13.
Treating the cognitive deficits of schizophrenia with alpha4beta2 neuronal nicotinic receptor agonists.
Curr Pharm Des
; 16(3): 309-22, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20109141
14.
Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties.
CNS Neurosci Ther
; 14(1): 65-82, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18482100
15.
An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo.
J Pharmacol Exp Ther
; 323(1): 294-307, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17625074
16.
4-amino-5-aryl-6-arylethynylpyrimidines: structure-activity relationships of non-nucleoside adenosine kinase inhibitors.
Bioorg Med Chem
; 15(4): 1586-605, 2007 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17197188
17.
Synthesis and biological evaluation of 6,7-disubstituted 4-aminopyrido[2,3-d]pyrimidines as adenosine kinase inhibitors.
Bioorg Med Chem Lett
; 15(11): 2803-7, 2005 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15911258
18.
5-(3-Bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine: structure-activity relationships of 7-substituted heteroaryl analogs as non-nucleoside adenosine kinase inhibitors.
Bioorg Med Chem
; 13(11): 3705-20, 2005 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15863000