Detalhe da pesquisa
1.
Presenilin-1 ΔE9 mutation associated sarcoplasmic reticulum leak alters [Ca2+]i distribution in human iPSC-derived cardiomyocytes.
J Mol Cell Cardiol
; 193: 78-87, 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38851626
2.
Translational investigation of electrophysiology in hypertrophic cardiomyopathy.
J Mol Cell Cardiol
; 157: 77-89, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33957110
3.
Arrhythmia Mechanisms in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
J Cardiovasc Pharmacol
; 77(3): 300-316, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33323698
4.
Refractoriness in human atria: Time and voltage dependence of sodium channel availability.
J Mol Cell Cardiol
; 101: 26-34, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27773652
5.
Calcium signalling in developing cardiomyocytes: implications for model systems and disease.
J Physiol
; 593(5): 1047-63, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25641733
6.
Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2.
Am J Physiol Heart Circ Physiol
; 309(3): H481-9, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26055791
7.
In silico screening of the key cellular remodeling targets in chronic atrial fibrillation.
PLoS Comput Biol
; 10(5): e1003620, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24853123
8.
Variable t-tubule organization and Ca2+ homeostasis across the atria.
Am J Physiol Heart Circ Physiol
; 307(4): H609-20, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24951751
9.
Investigations of the Navß1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.
Am J Physiol Heart Circ Physiol
; 306(8): H1204-12, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24561865
10.
NS5806 partially restores action potential duration but fails to ameliorate calcium transient dysfunction in a computational model of canine heart failure.
Europace
; 16 Suppl 4: iv46-iv55, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25362170
11.
In silico study of the mechanisms of hypoxia and contractile dysfunction during ischemia and reperfusion of hiPSC cardiomyocytes.
Dis Model Mech
; 17(4)2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38516812
12.
Building blocks of microphysiological system to model physiology and pathophysiology of human heart.
Front Physiol
; 14: 1213959, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37485060
13.
Human induced pluripotent stem cell-derived cardiomyocytes as an electrophysiological model: Opportunities and challenges-The Hamburg perspective.
Front Physiol
; 14: 1132165, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36875015
14.
Impact of sarcoplasmic reticulum calcium release on calcium dynamics and action potential morphology in human atrial myocytes: a computational study.
PLoS Comput Biol
; 7(1): e1001067, 2011 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21298076
15.
Altered contractility in mutation-specific hypertrophic cardiomyopathy: A mechano-energetic in silico study with pharmacological insights.
Front Physiol
; 13: 1010786, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36388127
16.
Computational cardiac physiology for new modelers: Origins, foundations, and future.
Acta Physiol (Oxf)
; 236(2): e13865, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35959512
17.
Regulation of APD and Force by the Na+/Ca2+ Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue.
Cells
; 11(15)2022 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35954268
18.
Ca2+-calmodulin-dependent protein kinase II represses cardiac transcription of the L-type calcium channel alpha(1C)-subunit gene (Cacna1c) by DREAM translocation.
J Physiol
; 589(Pt 11): 2669-86, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21486818
19.
A mathematical model of hiPSC cardiomyocytes electromechanics.
Physiol Rep
; 9(22): e15124, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34825519
20.
Comparison of the Simulated Response of Three in Silico Human Stem Cell-Derived Cardiomyocytes Models and in Vitro Data Under 15 Drug Actions.
Front Pharmacol
; 12: 604713, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33841140