Detalhe da pesquisa
1.
Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements.
PLoS Pathog
; 19(2): e1011168, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36812267
2.
Target Cell Activation of a Structurally Novel NOD-Like Receptor Pyrin Domain-Containing Protein 3 Inhibitor NT-0796 Enhances Potency.
J Pharmacol Exp Ther
; 388(3): 798-812, 2024 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253384
3.
The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.
Nat Immunol
; 13(9): 823-31, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863753
4.
Elarekibep (PRS-060/AZD1402), a new class of inhaled Anticalin medicine targeting IL-4Ra for type 2 endotype asthma.
J Allergy Clin Immunol
; 151(4): 966-975, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36592703
5.
Oxysterols Modify NLRP2 in Epithelial Cells, Identifying a Mediator of Ozone-induced Inflammation.
Am J Respir Cell Mol Biol
; 65(5): 500-512, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34126877
6.
Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.
Nature
; 527(7579): 477-83, 2015 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26550826
7.
Metabolism of Inorganic Arsenic in Mice Lacking Genes Encoding GST-P, GST-M, and GST-T.
Chem Res Toxicol
; 33(8): 2043-2046, 2020 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32700902
8.
Lipopolysaccharide Potentiates Insulin-Driven Hypoglycemic Shock.
J Immunol
; 199(10): 3634-3643, 2017 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29038248
9.
Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family.
Drug Metab Dispos
; 43(12): 1838-46, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26354949
10.
Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.
EMBO Rep
; 14(10): 900-6, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24008845
11.
Mice lacking three Loci encoding 14 glutathione transferase genes: a novel tool for assigning function to the GSTP, GSTM, and GSTT families.
Drug Metab Dispos
; 42(6): 1074-83, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24658454
12.
Prostaglandin E(2) produced by the lung augments the effector phase of allergic inflammation.
J Immunol
; 188(8): 4093-102, 2012 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22412193
13.
NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice.
J Immunol
; 189(4): 2006-16, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22753929
14.
Analysis of NLRP3 in the development of allergic airway disease in mice.
J Immunol
; 188(6): 2884-93, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22323538
15.
Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases.
Cell Rep
; 43(3): 113852, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38427558
16.
Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1H-pyrazol-4-yl)({[(2S)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational Framework.
ACS Pharmacol Transl Sci
; 7(5): 1438-1456, 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38751618
17.
Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
J Exp Med
; 204(6): 1383-93, 2007 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-17517966
18.
Enhanced mast cell activation in mice deficient in the A2b adenosine receptor.
J Exp Med
; 204(1): 117-28, 2007 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17200408
19.
The knockout mouse project.
Nat Genet
; 36(9): 921-4, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15340423
20.
Fate of arsenicals in mice carrying the human AS3MT gene exposed to environmentally relevant levels of arsenite in drinking water.
Sci Rep
; 13(1): 3660, 2023 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36871058