[Biosynthesis of nitric oxide and its function in organism]. / Biosynteza tlenku azotu i jego funkcje w organizmie.

Nitric oxide (NO) is a gas with diverse biological activities produced from L-arginine by nitric oxide synthetase (NOS). This article provides a short overview of the basic function of NO which takes part in smooth muscle relaxation, neurotransmission, modulation of inflammation in a number of tissues and pathological conditions. The discovery of these new physiological and pathological pathways allows for better understanding of many complex processes. It opens a new field for better treatment of many diseases.

[The role of nitric oxide in physiology and pathogenesis of ocular diseases]. / Udzial tlenku azotu w procesach fizjologicznych i patologicznych zachodzacych w oku.

Nitric oxide (NO) is a gas with diverse biological activities produced from arginine by nitric oxide synthetase (NOS). The loss of retinal ganglion cells is a hallmark of many ophthalmic diseases including glaucoma, retinal ischemia due to central artery occlusion and anterior ischemic optic neuropathy. It may well be significant in optic neuritis, optic nerve, trauma and AIDS. NO appears to be involved in the regulation of intraocular pressure, in the modulation of ocular blood flow and in apoptosis. This article gives a short and simplified overview of the biochemistry of NO and its role in physiology and pathogenesis of ocular diseases.