Detalhe da pesquisa
1.
Genetic analysis of the Candida albicans biofilm transcription factor network using simple and complex haploinsufficiency.
PLoS Genet
; 13(8): e1006948, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28793308
2.
The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis.
Antimicrob Agents Chemother
; 60(12): 7115-7127, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27645246
3.
Candida albicans triggers NLRP3-mediated pyroptosis in macrophages.
Eukaryot Cell
; 13(2): 329-40, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24376002
4.
Cryptococcus neoformans phosphoinositide-dependent kinase 1 (PDK1) ortholog is required for stress tolerance and survival in murine phagocytes.
Eukaryot Cell
; 12(1): 12-22, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23087368
5.
A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosis.
Eukaryot Cell
; 12(2): 278-87, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23243064
6.
The Spx regulator modulates stress responses and virulence in Enterococcus faecalis.
Infect Immun
; 80(7): 2265-75, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22508863
7.
A Genome-Wide Screen of Deletion Mutants in the Filamentous Saccharomyces cerevisiae Background Identifies Ergosterol as a Direct Trigger of Macrophage Pyroptosis.
mBio
; 9(4)2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30065091
8.
Systematic Complex Haploinsufficiency-Based Genetic Analysis of Candida albicans Transcription Factors: Tools and Applications to Virulence-Associated Phenotypes.
G3 (Bethesda)
; 8(4): 1299-1314, 2018 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29472308
9.
High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis.
mBio
; 9(4)2018 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131363
10.
Antitumor/Antifungal Celecoxib Derivative AR-12 is a Non-Nucleoside Inhibitor of the ANL-Family Adenylating Enzyme Acetyl CoA Synthetase.
ACS Infect Dis
; 2(4): 268-280, 2016 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27088128
11.
Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo.
mBio
; 5(1): e00765-13, 2014 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24520056
12.
Candida albicans morphogenesis is not required for macrophage interleukin 1ß production.
mBio
; 4(1): e00433-12, 2012 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23269828