Pesquisa | BVS IEC

1.

Small Molecule Screening Strategies from Lead Identification to Validation.

Kostic, Milka.

J Vis Exp ; (191)2023 01 20.

Artigo em Inglês | MEDLINE | ID: mdl-37602881

2.

Target 2035 - update on the quest for a probe for every protein.

Müller, Susanne; Ackloo, Suzanne; Al Chawaf, Arij; Al-Lazikani, Bissan; Antolin, Albert; Baell, Jonathan B; Beck, Hartmut; Beedie, Shaunna; Betz, Ulrich A K; Bezerra, Gustavo Arruda; Brennan, Paul E; Brown, David; Brown, Peter J; Bullock, Alex N; Carter, Adrian J; Chaikuad, Apirat; Chaineau, Mathilde; Ciulli, Alessio; Collins, Ian; Dreher, Jan; Drewry, David; Edfeldt, Kristina; Edwards, Aled M; Egner, Ursula; Frye, Stephen V; Fuchs, Stephen M; Hall, Matthew D; Hartung, Ingo V; Hillisch, Alexander; Hitchcock, Stephen H; Homan, Evert; Kannan, Natarajan; Kiefer, James R; Knapp, Stefan; Kostic, Milka; Kubicek, Stefan; Leach, Andrew R; Lindemann, Sven; Marsden, Brian D; Matsui, Hisanori; Meier, Jordan L; Merk, Daniel; Michel, Maurice; Morgan, Maxwell R; Mueller-Fahrnow, Anke; Owen, Dafydd R; Perry, Benjamin G; Rosenberg, Saul H; Saikatendu, Kumar Singh; Schapira, Matthieu.

RSC Med Chem ; 13(1): 13-21, 2022 Jan 27.

Artigo em Inglês | MEDLINE | ID: mdl-35211674

3.

Fragment-based covalent ligand discovery.

Lu, Wenchao; Kostic, Milka; Zhang, Tinghu; Che, Jianwei; Patricelli, Matthew P; Jones, Lyn H; Chouchani, Edward T; Gray, Nathanael S.

RSC Chem Biol ; 2(2): 354-367, 2021 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-34458789

4.

Correction: Fragment-based covalent ligand discovery.

Lu, Wenchao; Kostic, Milka; Zhang, Tinghu; Che, Jianwei; Patricelli, Matthew P; Jones, Lyn H; Chouchani, Edward T; Gray, Nathanael S.

RSC Chem Biol ; 2(2): 670-671, 2021 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-34459829

5.

Critical Assessment of Targeted Protein Degradation as a Research Tool and Pharmacological Modality.

Kostic, Milka; Jones, Lyn H.

Trends Pharmacol Sci ; 41(5): 305-317, 2020 05.

Artigo em Inglês | MEDLINE | ID: mdl-32222318

6.

Exploring Targeted Degradation Strategy for Oncogenic KRAS^G12C.

Zeng, Mei; Xiong, Yuan; Safaee, Nozhat; Nowak, Radoslaw P; Donovan, Katherine A; Yuan, Christine J; Nabet, Behnam; Gero, Thomas W; Feru, Frederic; Li, Lianbo; Gondi, Sudershan; Ombelets, Lincoln J; Quan, Chunshan; Jänne, Pasi A; Kostic, Milka; Scott, David A; Westover, Kenneth D; Fischer, Eric S; Gray, Nathanael S.

Cell Chem Biol ; 27(1): 19-31.e6, 2020 01 16.

Artigo em Inglês | MEDLINE | ID: mdl-31883964

7.

Recent Advances in Selective and Irreversible Covalent Ligand Development and Validation.

Zhang, Tinghu; Hatcher, John M; Teng, Mingxing; Gray, Nathanael S; Kostic, Milka.

Cell Chem Biol ; 26(11): 1486-1500, 2019 11 21.

Artigo em Inglês | MEDLINE | ID: mdl-31631011

8.

Hydrogen-deuterium exchange strategy for delineation of contact sites in protein complexes.

Dyson, H Jane; Kostic, Milka; Liu, Jeff; Martinez-Yamout, Maria A.

FEBS Lett ; 582(10): 1495-500, 2008 Apr 30.

Artigo em Inglês | MEDLINE | ID: mdl-18396165

9.

Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53.

Kostic, Milka; Matt, Theresia; Martinez-Yamout, Maria A; Dyson, H Jane; Wright, Peter E.

J Mol Biol ; 363(2): 433-50, 2006 Oct 20.

Artigo em Inglês | MEDLINE | ID: mdl-16965791

10.

Call for Special Issue Papers: New Modalities in Chemical Probes and Pharmacological Tools in Drug Discovery.

Kostic, Milka; Melancon, Bruce J.

Assay Drug Dev Technol ; 20(3): 103-104, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35363579

11.

Call for Special Issue Papers: Chemical Probes and Pharmacological Tools for Kinase Signaling.

Kostic, Milka; Melancon, Bruce J.

Assay Drug Dev Technol ; 2022 Feb 03.

Artigo em Inglês | MEDLINE | ID: mdl-35394354

12.

Call for Special Issue Papers: Special Issue on High-throughput Technologies for the Discovery and Development of Chemical Probes and Pharmacological Tools.

Kostic, Milka; Melancon, Bruce J.

Assay Drug Dev Technol ; 2022 Feb 03.

Artigo em Inglês | MEDLINE | ID: mdl-35394358

13.

From Glioblastoma to Hepatitis C: It's a Metabolism Thing.

Kostic, Milka.

Cell Chem Biol ; 23(11): 1315-1316, 2016 Nov 17.

Artigo em Inglês | MEDLINE | ID: mdl-27863215

14.

RAF Inhibitors, Fishing Bacterial Transporters Out of Metagenomes, and Yeast-Based, Industrial Scale Production of Isoprenoids.

Kostic, Milka.

Cell Chem Biol ; 23(10): 1171-1172, 2016 Oct 20.

Artigo em Inglês | MEDLINE | ID: mdl-27768864

15.

Biasing Opioid Receptors and Cholesterol as a Player in Developmental Biology.

Kostic, Milka.

Cell Chem Biol ; 23(9): 1039-1040, 2016 Sep 22.

Artigo em Inglês | MEDLINE | ID: mdl-27662248

16.

Stem Cell Hydrogel, Jump-Starting Zika Drug Discovery, and Engineering RNA Recognition.

Kostic, Milka.

Cell Chem Biol ; 23(8): 885-6, 2016 08 18.

Artigo em Inglês | MEDLINE | ID: mdl-27541191

17.

Structural genomics.

Sali, Andrej; Lima, Christopher D; Kostic, Milka.

Structure ; 15(11): 1341, 2007 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-17997955

18.

A Shout Out to Chemical Biology, a Multidisciplinary Field Par Excellence.

Kostic, Milka.

Cell Chem Biol ; 24(4): 427, 2017 04 20.

Artigo em Inglês | MEDLINE | ID: mdl-28431221

19.

Chemical Biology as a Driver of Innovation in Cancer Research and Drug Discovery.

Kostic, Milka; Arkin, Michelle.

Cell Chem Biol ; 24(9): 1057, 2017 09 21.

Artigo em Inglês | MEDLINE | ID: mdl-28938086

20.

That's a Wrap!

Kostic, Milka.

Cell Chem Biol ; 23(12): 1439, 2016 Dec 22.

Artigo em Inglês | MEDLINE | ID: mdl-28009973

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Small Molecule Screening Strategies from Lead Identification to Validation.

Target 2035 - update on the quest for a probe for every protein.

Fragment-based covalent ligand discovery.

Correction: Fragment-based covalent ligand discovery.

Critical Assessment of Targeted Protein Degradation as a Research Tool and Pharmacological Modality.

Exploring Targeted Degradation Strategy for Oncogenic KRAS^G12C.

Recent Advances in Selective and Irreversible Covalent Ligand Development and Validation.

Hydrogen-deuterium exchange strategy for delineation of contact sites in protein complexes.

Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53.

Call for Special Issue Papers: New Modalities in Chemical Probes and Pharmacological Tools in Drug Discovery.

Call for Special Issue Papers: Chemical Probes and Pharmacological Tools for Kinase Signaling.

Call for Special Issue Papers: Special Issue on High-throughput Technologies for the Discovery and Development of Chemical Probes and Pharmacological Tools.

From Glioblastoma to Hepatitis C: It's a Metabolism Thing.

RAF Inhibitors, Fishing Bacterial Transporters Out of Metagenomes, and Yeast-Based, Industrial Scale Production of Isoprenoids.

Biasing Opioid Receptors and Cholesterol as a Player in Developmental Biology.

Stem Cell Hydrogel, Jump-Starting Zika Drug Discovery, and Engineering RNA Recognition.

Structural genomics.

A Shout Out to Chemical Biology, a Multidisciplinary Field Par Excellence.

Chemical Biology as a Driver of Innovation in Cancer Research and Drug Discovery.

That's a Wrap!