Detalhe da pesquisa
1.
Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer.
Pharmacol Res
; 189: 106683, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36736415
2.
UV Laser-Induced Phototransformations of Matrix-Isolated 5-Chloro-3-nitro-2-hydroxyacetophenone.
Int J Mol Sci
; 24(2)2023 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36675062
3.
Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor.
Molecules
; 28(13)2023 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446625
4.
N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation.
Molecules
; 27(23)2022 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36500256
5.
Structure, Spectra and Photochemistry of 2-Amino-4-Methylthiazole: FTIR Matrix Isolation and Theoretical Studies.
Molecules
; 27(12)2022 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35745029
6.
New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators.
Molecules
; 26(11)2021 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34071439
7.
Polymorphism and Conformational Equilibrium of Nitro-Acetophenone in Solid State and under Matrix Conditions.
Molecules
; 26(11)2021 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34067498
8.
Synthesis of the Major Mammalian Metabolites of THCV.
J Nat Prod
; 83(7): 2060-2065, 2020 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32649196
9.
Alterations in Anandamide Synthesis and Degradation during Osteoarthritis Progression in an Animal Model.
Int J Mol Sci
; 21(19)2020 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33036283
10.
Molecular Understanding of the Activation of CB1 and Blockade of TRPV1 Receptors: Implications for Novel Treatment Strategies in Osteoarthritis.
Int J Mol Sci
; 19(2)2018 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29364174
11.
The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain.
Pharmacol Res
; 111: 251-263, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27326920
12.
Description of Novel Molecular Factors in Lumbar DRGs and Spinal Cord Factors Underlying Development of Neuropathic Pain Component in the Animal Model of Osteoarthritis.
Mol Neurobiol
; 61(3): 1580-1592, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37731080
13.
Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo.
ACS Chem Neurosci
; 15(5): 955-971, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38372253
14.
Novel pyrrole based CB2 agonists: New insights on CB2 receptor role in regulating neurotransmitters' tone.
Eur J Med Chem
; 269: 116298, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38493727
15.
The Impact of JWH-133 on Articular Cartilage Regeneration in Osteoarthritis Via Metalloproteinase 13-Dependent Mechanism.
Cannabis Cannabinoid Res
; 8(5): 779-789, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36318796
16.
N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R).
Eur J Med Chem
; 248: 115109, 2023 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36657299
17.
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase.
J Med Chem
; 66(1): 235-250, 2023 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36542836
18.
Sodium Monoiodoacetate Dose-Dependent Changes in Matrix Metalloproteinases and Inflammatory Components as Prognostic Factors for the Progression of Osteoarthritis.
Front Pharmacol
; 12: 643605, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33995052
19.
CB2 agonism controls pain and subchondral bone degeneration induced by mono-iodoacetate: Implications GPCR functional bias and tolerance development.
Biomed Pharmacother
; 136: 111283, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33482616
20.
Modulation of Endocannabinoid Tone in Osteoblastic Differentiation of MC3T3-E1 Cells and in Mouse Bone Tissue over Time.
Cells
; 10(5)2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34068882