Detalhe da pesquisa
1.
Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease.
Ann Neurol
; 93(6): 1158-1172, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36843330
2.
Sediment temperature characteristics and their relation to distribution patterns of two sentinel crab species in intertidal flats in western Japan.
Sci Rep
; 14(1): 861, 2024 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38195849
3.
Development and application of a second-generation multilingual tool for invasion risk screening of non-native terrestrial plants.
Sci Total Environ
; 917: 170475, 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38296092
4.
A combined physiologically-based pharmacokinetic and quantitative systems pharmacology model for modeling amyloid aggregation in Alzheimer's disease.
CPT Pharmacometrics Syst Pharmacol
; 12(4): 444-461, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36632701
5.
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease.
Nat Med
; 29(8): 1954-1963, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37443334
6.
Population pharmacokinetic-pharmacodynamic analyses of amyloid positron emission tomography and plasma biomarkers for lecanemab in subjects with early Alzheimer's disease.
CPT Pharmacometrics Syst Pharmacol
; 11(12): 1578-1591, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36165093
7.
Lecanemab in patients with early Alzheimer's disease: detailed results on biomarker, cognitive, and clinical effects from the randomized and open-label extension of the phase 2 proof-of-concept study.
Alzheimers Res Ther
; 14(1): 191, 2022 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36544184
8.
Fully automated and highly specific plasma ß-amyloid immunoassays predict ß-amyloid status defined by amyloid positron emission tomography with high accuracy.
Alzheimers Res Ther
; 14(1): 86, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35739591
9.
Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment.
JAMA Netw Open
; 5(4): e228392, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35446396
10.
A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aß protofibril antibody.
Alzheimers Res Ther
; 13(1): 80, 2021 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33865446
11.
The ß-Secretase BACE1 in Alzheimer's Disease.
Biol Psychiatry
; 89(8): 745-756, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32223911
12.
A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans.
Hum Mol Genet
; 17(19): 2997-3009, 2008 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18617532
13.
Habitat suitability maps for juvenile tri-spine horseshoe crabs in Japanese intertidal zones: A model approach using unmanned aerial vehicles and the Structure from Motion technique.
PLoS One
; 15(12): e0244494, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33362230
14.
Correction to: A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aß protofibril antibody.
Alzheimers Res Ther
; 14(1): 70, 2022 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35598024
15.
Network dysfunction in α-synuclein transgenic mice and human Lewy body dementia.
Ann Clin Transl Neurol
; 2(11): 1012-28, 2015 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26732627
16.
Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila.
Neurosci Lett
; 336(3): 155-8, 2003 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-12505616
17.
Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits.
PLoS One
; 7(9): e45881, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23029293
18.
Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease.
PLoS One
; 6(12): e29257, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22206005
19.
Proteomics of Caenorhabditis elegans over-expressing human alpha-synuclein analyzed by fluorogenic derivatization-liquid chromatography/tandem mass spectrometry: identification of actin and several ribosomal proteins as negative markers at early Parkinson's disease stages.
Biomed Chromatogr
; 22(3): 232-4, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17939164
20.
Familial Parkinson mutant alpha-synuclein causes dopamine neuron dysfunction in transgenic Caenorhabditis elegans.
J Biol Chem
; 281(1): 334-40, 2006 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16260788