Detalhe da pesquisa
1.
Engineering PD-1-targeted small protein variants for in vitro diagnostics and in vivo PET imaging.
J Transl Med
; 22(1): 426, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38711085
2.
Jasmone Is a Ligand-Selective Allosteric Antagonist of Aryl Hydrocarbon Receptor (AhR).
Int J Mol Sci
; 24(21)2023 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37958638
3.
Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics.
Bioorg Chem
; 109: 104661, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33636438
4.
Antimigraine Drug Avitriptan Is a Ligand and Agonist of Human Aryl Hydrocarbon Receptor That Induces CYP1A1 in Hepatic and Intestinal Cells.
Int J Mol Sci
; 21(8)2020 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32316498
5.
Gut Microbial Catabolites of Tryptophan Are Ligands and Agonists of the Aryl Hydrocarbon Receptor: A Detailed Characterization.
Int J Mol Sci
; 21(7)2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283770
6.
In vitro analysis of itraconazole cis-diastereoisomers inhibition of nine cytochrome P450 enzymes: stereoselective inhibition of CYP3A.
Xenobiotica
; 49(1): 36-42, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29320899
7.
Interaction of isoflavonoids with human liver microsomal cytochromes P450: inhibition of CYP enzyme activities.
Xenobiotica
; 47(4): 324-331, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27312150
8.
Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity.
Molecules
; 22(11)2017 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29099769
9.
Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions.
Molecules
; 22(4)2017 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28338641
10.
Enantiospecific effects of chiral drugs on cytochrome P450 inhibition in vitro.
Xenobiotica
; 46(4): 315-24, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26338061
11.
Preclinical characterisation of gallium-68 labeled ferrichrome siderophore stereoisomers for PET imaging applications.
EJNMMI Radiopharm Chem
; 9(1): 20, 2024 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38436776
12.
Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice.
Nat Commun
; 14(1): 2728, 2023 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37169746
13.
Bacterial Indole as a Multifunctional Regulator of Klebsiella oxytoca Complex Enterotoxicity.
mBio
; 13(1): e0375221, 2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35073747
14.
Intestinal interplay of quorum sensing molecules and human receptors.
Biochimie
; 189: 108-119, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34186126
15.
Indole microbial intestinal metabolites expand the repertoire of ligands and agonists of the human pregnane X receptor.
Toxicol Lett
; 334: 87-93, 2020 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33002526
16.
Mono-methylindoles induce CYP1A genes and inhibit CYP1A1 enzyme activity in human hepatocytes and HepaRG cells.
Toxicol Lett
; 313: 66-76, 2019 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31201936
17.
Effects of Flavored Nonalcoholic Beverages on Transcriptional Activities of Nuclear and Steroid Hormone Receptors: Proof of Concept for Novel Reporter Cell Line PAZ-PPARg.
J Agric Food Chem
; 66(45): 12066-12078, 2018 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30394742
18.
The inhibitory effects of ß-caryophyllene, ß-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro.
Chem Biol Interact
; 278: 123-128, 2017 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29074051
19.
Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450.
Toxicol Lett
; 262: 173-186, 2016 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27732883
20.
Dual effects of ketoconazole cis-enantiomers on CYP3A4 in human hepatocytes and HepG2 Cells.
PLoS One
; 9(10): e111286, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25343516