Detalhe da pesquisa
1.
Reversed isoniazids: Design, synthesis and evaluation against Mycobacterium tuberculosis.
Bioorg Med Chem
; 26(4): 833-844, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29373270
2.
New Verapamil Analogs Inhibit Intracellular Mycobacteria without Affecting the Functions of Mycobacterium-Specific T Cells.
Antimicrob Agents Chemother
; 60(3): 1216-25, 2015 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26643325
3.
Synthesis of new verapamil analogues and their evaluation in combination with rifampicin against Mycobacterium tuberculosis and molecular docking studies in the binding site of efflux protein Rv1258c.
Bioorg Med Chem Lett
; 24(14): 2985-90, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24894561
4.
Pyrido-Dibemequine Metabolites Exhibit Improved Druglike Features, Inhibit Hemozoin Formation in Plasmodium falciparum, and Synergize with Clinical Antimalarials.
ACS Infect Dis
; 9(3): 653-667, 2023 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36802523
5.
Synthesis, docking and in vitro antimalarial evaluation of bifunctional hybrids derived from ß-lactams and 7-chloroquinoline using click chemistry.
Bioorg Med Chem Lett
; 22(1): 57-61, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22172698
6.
Novel 3-Trifluoromethyl-1,2,4-oxadiazole Analogues of Astemizole with Multi-stage Antiplasmodium Activity and In Vivo Efficacy in a Plasmodium berghei Mouse Malaria Infection Model.
J Med Chem
; 65(24): 16695-16715, 2022 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36507890
7.
Structure-Activity Relationship Studies Reveal New Astemizole Analogues Active against Plasmodium falciparum In Vitro.
ACS Med Chem Lett
; 12(8): 1333-1341, 2021 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34413963
8.
New Amidated 3,6-Diphenylated Imidazopyridazines with Potent Antiplasmodium Activity Are Dual Inhibitors of Plasmodium Phosphatidylinositol-4-kinase and cGMP-Dependent Protein Kinase.
ACS Infect Dis
; 7(1): 34-46, 2021 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33319990
9.
Multistage Antiplasmodium Activity of Astemizole Analogues and Inhibition of Hemozoin Formation as a Contributor to Their Mode of Action.
ACS Infect Dis
; 5(2): 303-315, 2019 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30525439
10.
Design, Synthesis, and Evaluation of Novel Hybrid Efflux Pump Inhibitors for Use against Mycobacterium tuberculosis.
ACS Infect Dis
; 2(10): 714-725, 2016 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27737555