Detalhe da pesquisa
1.
A first-in-human study of the novel immunology antibody-drug conjugate, ABBV-3373, in healthy participants.
Br J Clin Pharmacol
; 90(1): 189-199, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37596703
2.
Genetic markers associated with clinical and radiographic response in adalimumab plus methotrexate- or methotrexate-treated rheumatoid arthritis patients in OPTIMA.
Clin Exp Rheumatol
; 37(5): 783-790, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30963994
3.
Testing treat-to-target outcomes with initial methotrexate monotherapy compared with initial tumour necrosis factor inhibitor (adalimumab) plus methotrexate in early rheumatoid arthritis.
Ann Rheum Dis
; 77(2): 289-292, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29146743
4.
Effect of adalimumab on the work-related outcomes scores in patients with early rheumatoid arthritis receiving methotrexate.
Rheumatology (Oxford)
; 55(8): 1458-65, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27114561
5.
Adjustment of therapy in rheumatoid arthritis on the basis of achievement of stable low disease activity with adalimumab plus methotrexate or methotrexate alone: the randomised controlled OPTIMA trial.
Lancet
; 383(9914): 321-32, 2014 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24168956
6.
Efficacy and safety of ascending methotrexate dose in combination with adalimumab: the randomised CONCERTO trial.
Ann Rheum Dis
; 74(6): 1037-44, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550168
7.
Final 10-year effectiveness and safety results from study DE020: adalimumab treatment in patients with rheumatoid arthritis and an inadequate response to standard therapy.
Rheumatology (Oxford)
; 54(12): 2188-97, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26199453
8.
Maintenance of improvement in spinal mobility, physical function and quality of life in patients with ankylosing spondylitis after 5 years in a clinical trial of adalimumab.
Rheumatology (Oxford)
; 54(7): 1210-9, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25541333
9.
Adalimumab, a human anti-TNF monoclonal antibody, outcome study for the prevention of joint damage in Japanese patients with early rheumatoid arthritis: the HOPEFUL 1 study.
Ann Rheum Dis
; 73(3): 536-43, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23316080
10.
Recovery of clinical but not radiographic outcomes by the delayed addition of adalimumab to methotrexate-treated Japanese patients with early rheumatoid arthritis: 52-week results of the HOPEFUL-1 trial.
Rheumatology (Oxford)
; 53(5): 904-13, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24441150
11.
Clinical, functional and radiographic consequences of achieving stable low disease activity and remission with adalimumab plus methotrexate or methotrexate alone in early rheumatoid arthritis: 26-week results from the randomised, controlled OPTIMA study.
Ann Rheum Dis
; 72(1): 64-71, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22562973
12.
Efficacy and Safety of ABBV-3373, a Novel Anti-Tumor Necrosis Factor Glucocorticoid Receptor Modulator Antibody-Drug Conjugate, in Adults with Moderate-to-Severe Rheumatoid Arthritis Despite Methotrexate Therapy: A Randomized, Double-Blind, Active-Controlled Proof-of-Concept Phase IIa Trial.
Arthritis Rheumatol
; 75(6): 879-889, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36512671
13.
Is the Health Utilities Index 3 valid for patients with ankylosing spondylitis?
Value Health
; 14(1): 160-5, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21211498
14.
Clinical manifestations and responsiveness to adalimumab are similar in patients with ankylosing spondylitis with and without concomitant psoriasis.
Rheumatology (Oxford)
; 49(8): 1578-89, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20448079
15.
Validity, reliability and responsiveness of the Work Productivity and Activity Impairment Questionnaire in ankylosing spondylitis.
Rheumatology (Oxford)
; 49(4): 812-9, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20100797
16.
Safety and Effectiveness of Adalimumab in Patients With Polyarticular Course of Juvenile Idiopathic Arthritis: STRIVE Registry Seven-Year Interim Results.
Arthritis Care Res (Hoboken)
; 72(10): 1420-1430, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31421019
17.
Response to H Zeidler's comments on the CONCERTO study.
Ann Rheum Dis
; 73(8): e51, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24914070
18.
Adalimumab is effective and well tolerated in treating patients with ankylosing spondylitis who have advanced spinal fusion.
Rheumatology (Oxford)
; 48(5): 551-7, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19254918
19.
An open-label pilot study of the effectiveness of adalimumab in patients with rheumatoid arthritis and previous infliximab treatment: relationship to reasons for failure and anti-infliximab antibody status.
Clin Rheumatol
; 27(8): 1021-8, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18350329
20.
Low Hemoglobin and Radiographic Damage Progression in Early Rheumatoid Arthritis: Secondary Analysis From a Phase III Trial.
Arthritis Care Res (Hoboken)
; 70(6): 861-868, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28950430