Detalhe da pesquisa
1.
Sulfonylpiperazine compounds prevent Plasmodium falciparum invasion of red blood cells through interference with actin-1/profilin dynamics.
PLoS Biol
; 21(4): e3002066, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37053271
2.
Structure and function of Plasmodium actin II in the parasite mosquito stages.
PLoS Pathog
; 19(3): e1011174, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36877739
3.
High-resolution structures of malaria parasite actomyosin and actin filaments.
PLoS Pathog
; 18(4): e1010408, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377914
4.
Analysis of Plasmodium falciparum myosin B ATPase activity and structure in complex with the calmodulin-like domain of its light chain MLC-B.
J Biol Chem
; 298(12): 102634, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36273584
5.
Structure and function of an atypical homodimeric actin capping protein from the malaria parasite.
Cell Mol Life Sci
; 79(2): 125, 2022 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35132495
6.
Modeling and resistant alleles explain the selectivity of antimalarial compound 49c towards apicomplexan aspartyl proteases.
EMBO J
; 37(7)2018 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29519896
7.
A function of profilin in force generation during malaria parasite motility that is independent of actin binding.
J Cell Sci
; 134(5)2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32034083
8.
Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and fragmentation.
PLoS Biol
; 17(6): e3000315, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31199804
9.
Functional homo- and heterodimeric actin capping proteins from the malaria parasite.
Biochem Biophys Res Commun
; 525(3): 681-686, 2020 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32139121
10.
Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability.
Proc Natl Acad Sci U S A
; 114(40): 10636-10641, 2017 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923924
11.
The quaternary structure of human tyrosine hydroxylase: effects of dystonia-associated missense variants on oligomeric state and enzyme activity.
J Neurochem
; 148(2): 291-306, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30411798
12.
A unique profilin-actin interface is important for malaria parasite motility.
PLoS Pathog
; 13(5): e1006412, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28552953
13.
Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility.
J Biol Chem
; 292(43): 17857-17875, 2017 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28893907
14.
Structural and functional dissection of Toxoplasma gondii armadillo repeats only protein.
J Cell Sci
; 129(5): 1031-45, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26769898
15.
Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase.
BMC Biochem
; 18(1): 7, 2017 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28511668
16.
Structural differences explain diverse functions of Plasmodium actins.
PLoS Pathog
; 10(4): e1004091, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24743229
17.
Two independently folding units of Plasmodium profilin suggest evolution via gene fusion.
Cell Mol Life Sci
; 72(21): 4193-203, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26012696
18.
Structure of Toxoplasma gondii coronin, an actin-binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress.
FASEB J
; 28(11): 4729-47, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25114175
19.
Atomic resolution view into the structure-function relationships of the human myelin peripheral membrane protein P2.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 1): 165-76, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24419389
20.
Crystallization and preliminary structural characterization of the two actin isoforms of the malaria parasite.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 69(Pt 10): 1171-6, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24100575