Detalhe da pesquisa
1.
Disruption of mitochondrial quality control genes promotes caspase-resistant cell survival following apoptotic stimuli.
J Biol Chem
; 298(4): 101835, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35304098
2.
Functional Analysis of Immune Signature Genes in Th1* Memory Cells Links ISOC1 and Pyrimidine Metabolism to IFN-γ and IL-17 Production.
J Immunol
; 206(6): 1181-1193, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33547171
3.
Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis.
Mol Cell
; 57(1): 69-82, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25482509
4.
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.
Mol Cell
; 31(4): 557-569, 2008 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18691924
5.
Bax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranes.
PLoS Biol
; 10(9): e1001394, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23049480
6.
Olgotrelvir as a Single-Agent Treatment of Nonhospitalized Patients with Covid-19.
NEJM Evid
; 3(6): EVIDoa2400026, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38804790
7.
Olgotrelvir, a dual inhibitor of SARS-CoV-2 Mpro and cathepsin L, as a standalone antiviral oral intervention candidate for COVID-19.
Med
; 5(1): 42-61.e23, 2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38181791
8.
HIV-1 Fusion with CD4+ T cells Is Promoted by Proteins Involved in Endocytosis and Intracellular Membrane Trafficking.
Viruses
; 11(2)2019 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30691001
9.
Olgotrelvir, a dual inhibitor of SARS-CoV-2 Mpro and cathepsin L, as a standalone antiviral oral intervention candidate for COVID-19.
Med
; 5(2): 169-171, 2024 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38340710
10.
Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets.
Diabetes
; 52(4): 965-73, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12663468
11.
OPA1 expression in the normal rat retina and optic nerve.
J Comp Neurol
; 488(1): 1-10, 2005 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15912498
12.
Bioenergetics and cell death.
Ann N Y Acad Sci
; 1201: 50-7, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20649539
13.
Caspase-independent mitochondrial cell death results from loss of respiration, not cytotoxic protein release.
Mol Biol Cell
; 20(23): 4871-84, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19793916
14.
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.
EMBO J
; 25(16): 3900-11, 2006 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-16874299
15.
Cellular and subcellular calcium accumulation during glutamate-induced injury in cerebellar granule neurons.
J Neurochem
; 92(5): 1081-90, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15715659
16.
Excitotoxic injury to mitochondria isolated from cultured neurons.
J Biol Chem
; 280(32): 28894-902, 2005 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-15932874
17.
Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival.
J Biol Chem
; 280(49): 40398-401, 2005 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16207717
18.
Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state.
Biochem J
; 368(Pt 2): 545-53, 2002 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12180906