Detalhe da pesquisa
1.
Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis.
Cell
; 148(5): 988-1000, 2012 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22385963
2.
Calcium signals regulate the functional differentiation of thymic iNKT cells.
EMBO J
; 40(16): e107901, 2021 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34169542
3.
Disruption of mitochondrial quality control genes promotes caspase-resistant cell survival following apoptotic stimuli.
J Biol Chem
; 298(4): 101835, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35304098
4.
Phenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1.
PLoS Biol
; 17(6): e2004413, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31181072
5.
Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilization.
J Biol Chem
; 295(6): 1623-1636, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31901077
6.
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.
Mol Cell
; 31(4): 557-569, 2008 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18691924
7.
Bax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranes.
PLoS Biol
; 10(9): e1001394, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23049480
8.
Apoptosis regulation at the mitochondrial outer membrane.
J Cell Biochem
; 115(4): 632-40, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24453042
9.
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization.
Dev Cell
; 14(2): 193-204, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18267088
10.
BH3 domains other than Bim and Bid can directly activate Bax/Bak.
J Biol Chem
; 286(1): 491-501, 2011 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21041309
11.
Bcl-2-family proteins and the role of mitochondria in apoptosis.
Curr Opin Cell Biol
; 15(6): 691-9, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14644193
12.
Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins.
Proc Natl Acad Sci U S A
; 105(51): 20327-32, 2008 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19074266
13.
Cryo-Electron Microscopy to Study Bax Pores and MOMP.
Methods Mol Biol
; 1877: 247-256, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30536011
14.
Pro-apoptotic Bax molecules densely populate the edges of membrane pores.
Sci Rep
; 6: 27299, 2016 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27255832
15.
Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes.
Mol Biol Cell
; 26(2): 339-49, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25411335
16.
Diminished sensitivity of chronic lymphocytic leukemia cells to ABT-737 and ABT-263 due to albumin binding in blood.
Clin Cancer Res
; 16(16): 4217-25, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20601444
17.
Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation.
Mol Biol Cell
; 20(8): 2276-85, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19244344
18.
Caspase inhibition blocks cell death and results in cell cycle arrest in cytokine-deprived hematopoietic cells.
J Biol Chem
; 282(4): 2144-55, 2007 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-17102131
19.
PUMA couples the nuclear and cytoplasmic proapoptotic function of p53.
Science
; 309(5741): 1732-5, 2005 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16151013
20.
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
Mol Cell
; 17(4): 525-35, 2005 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15721256