1.
Dermatology
; 195(1): 52-3, 1997.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9267740
RESUMO
We report a patient with multiple sclerosis who was receiving subcutaneous injections of recombinant interferon beta. During the third month of treatment, painful necrotizing cutaneous lesions appeared at the injection sites. The possible pathogenesis of interferon-induced skin necrosis is discussed.
Assuntos
Adjuvantes Imunológicos/efeitos adversos , Interferon beta/efeitos adversos , Esclerose Múltipla/terapia , Pele/patologia , Adjuvantes Imunológicos/administração & dosagem , Adulto , Eritema/etiologia , Feminino , Humanos , Injeções Subcutâneas , Interferon beta/administração & dosagem , Necrose , Proteínas Recombinantes
2.
Dermatology
; 194(4): 358-60, 1997.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9252757
RESUMO
A case of cutaneous malakoplakia in an 81-year-old woman in reported. A reddish slowly growing plaque had appeared on her forehead 13 years previously. Histopathology revealed a dense dermal granulomatous infiltrate consisting of lymphocytes and numerous histiocytes containing Michaelis-Gutmann bodies. Ciprofloxacin treatment resulted in partial involution of the lesion.