Detalhe da pesquisa
1.
Finely-tuned regulation of AMP-activated protein kinase is crucial for human adult erythropoiesis.
Haematologica
; 104(5): 907-918, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30309849
2.
Comprehensive mutational profiling of core binding factor acute myeloid leukemia.
Blood
; 127(20): 2451-9, 2016 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26980726
3.
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Blood
; 126(11): 1346-56, 2015 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26186940
4.
Frequent ASXL2 mutations in acute myeloid leukemia patients with t(8;21)/RUNX1-RUNX1T1 chromosomal translocations.
Blood
; 124(9): 1445-9, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24973361
5.
Erythropoiesis and transferrin receptors.
Curr Opin Hematol
; 22(3): 193-8, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25767952
6.
Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.
Blood
; 122(20): 3521-32, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24014241
7.
Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form.
Haematologica
; 100(4): 458-65, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25637053
8.
Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes.
Blood
; 119(6): 1532-42, 2012 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22160620
9.
Mutation in TET2 in myeloid cancers.
N Engl J Med
; 360(22): 2289-301, 2009 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19474426
10.
Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis.
Blood
; 116(24): 5357-67, 2010 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20826723
11.
IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia.
Blood
; 116(20): 4240-50, 2010 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20671123
12.
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation.
Blood
; 116(20): 4262-73, 2010 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20668229
13.
PI3K and mTOR signaling pathways in cancer: new data on targeted therapies.
Curr Oncol Rep
; 14(2): 129-38, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22350330
14.
PAX2 is activated by estradiol in breast cancer cells of the luminal subgroup selectively, to confer a low invasive phenotype.
Mol Cancer
; 10: 148, 2011 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22168360
15.
Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.
Blood
; 114(8): 1618-27, 2009 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19458359
16.
TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).
Blood
; 114(15): 3285-91, 2009 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19666869
17.
TET2 mutations in secondary acute myeloid leukemias: a French retrospective study.
Haematologica
; 96(7): 1059-63, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21508122
18.
High levels of CD34+CD38low/-CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucemies Aigues et Maladies du Sang (GOELAMS) study.
Haematologica
; 96(12): 1792-8, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21933861
19.
Role of the PI3K/AKT and mTOR signaling pathways in acute myeloid leukemia.
Haematologica
; 95(5): 819-28, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19951971
20.
Autocrine IGF-1/IGF-1R signaling is responsible for constitutive PI3K/Akt activation in acute myeloid leukemia: therapeutic value of neutralizing anti-IGF-1R antibody.
Haematologica
; 95(3): 415-23, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20007139