Detalhe da pesquisa
1.
On Ternary Complex Stability in Protein Degradation: In Silico Molecular Glue Binding Affinity Calculations.
J Chem Inf Model
; 63(8): 2382-2392, 2023 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37037192
2.
Structure-based design and discovery of potent and selective lysine-specific demethylase 1 (LSD1) inhibitors.
Bioorg Med Chem Lett
; 29(1): 103-106, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30409536
3.
Structure-based design and discovery of potent and selective KDM5 inhibitors.
Bioorg Med Chem Lett
; 28(9): 1490-1494, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29627262
4.
Cereblon-based Bifunctional Degrader of SOS1, BTX-6654, Targets Multiple KRAS Mutations and Inhibits Tumor Growth.
Mol Cancer Ther
; 23(4): 407-420, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38224565
5.
Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1).
J Med Chem
; 63(23): 14522-14529, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33034194
6.
Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.
ACS Med Chem Lett
; 8(8): 869-874, 2017 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28835804
7.
RDEA119/BAY 869766: a potent, selective, allosteric inhibitor of MEK1/2 for the treatment of cancer.
Cancer Res
; 69(17): 6839-47, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19706763