Detalhe da pesquisa
1.
N-Acylethanolamine-hydrolyzing acid amidase inhibition increases colon N-palmitoylethanolamine levels and counteracts murine colitis.
FASEB J
; 29(2): 650-61, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25384424
2.
Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6.
Proc Natl Acad Sci U S A
; 110(43): 17558-63, 2013 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24101490
3.
3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis.
Bioorg Med Chem
; 21(17): 5383-94, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23849204
4.
The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action.
BMC Cancer
; 12: 92, 2012 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22429826
5.
Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation.
FASEB J
; 25(8): 2711-21, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21551239
6.
Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold.
Bioorg Med Chem
; 20(21): 6260-75, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23036333
7.
Lipid transport function is the main target of oral oleoylethanolamide to reduce adiposity in high-fat-fed mice.
J Lipid Res
; 52(7): 1373-82, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21515921
8.
Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase.
J Biol Chem
; 285(39): 29826-33, 2010 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20657015
9.
The endocannabinoid system links gut microbiota to adipogenesis.
Mol Syst Biol
; 6: 392, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20664638
10.
Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone.
Bioorg Med Chem Lett
; 21(24): 7321-4, 2011 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22056744
11.
Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imaging.
Bioorg Med Chem
; 19(15): 4499-505, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21737287
12.
New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitis.
Bioorg Med Chem
; 19(12): 3777-86, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21612933
13.
Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling.
Chembiochem
; 11(2): 218-27, 2010 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19957260
14.
Influence of chronic bromocriptine and levodopa administration on cerebral type 1 cannabinoid receptor binding.
Synapse
; 64(8): 617-23, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20340169
15.
Radiosynthesis, in vitro and in vivo evaluation of 123I-labeled anandamide analogues for mapping brain FAAH.
Bioorg Med Chem
; 17(1): 49-56, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19054678
16.
Identification of a novel endocannabinoid-hydrolyzing enzyme expressed by microglial cells.
J Neurosci
; 27(11): 2883-9, 2007 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17360910
17.
Reciprocal influences of CB1 cannabinoid receptor agonists on ERK and JNK signalling in N1E-115 cells.
FEBS Lett
; 582(28): 3861-7, 2008 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-18950629
18.
CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay.
Chembiochem
; 9(16): 2704-10, 2008 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-18855964
19.
An in vivo [18F]MK-9470 microPET study of type 1 cannabinoid receptor binding in Wistar rats after chronic administration of valproate and levetiracetam.
Neuropharmacology
; 54(7): 1103-6, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18423778
20.
Labelling and biological evaluation of [(11)C]methoxy-Sch225336: a radioligand for the cannabinoid-type 2 receptor.
Nucl Med Biol
; 35(7): 793-800, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18848664