Detalhe da pesquisa
1.
Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating.
Cell
; 165(2): 434-448, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26997484
2.
Modulators of Kv3 Potassium Channels Rescue the Auditory Function of Fragile X Mice.
J Neurosci
; 39(24): 4797-4813, 2019 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30936239
3.
Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brain stem neurons.
J Neurophysiol
; 116(1): 106-21, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27052580
4.
A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons.
J Pharmacol Exp Ther
; 354(3): 251-60, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085652
5.
Mechanisms contributing to central excitability changes during hearing loss.
Proc Natl Acad Sci U S A
; 109(21): 8292-7, 2012 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566618
6.
The binding and mechanism of a positive allosteric modulator of Kv3 channels.
Nat Commun
; 15(1): 2533, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38514618
7.
Targeted therapy improves cellular dysfunction, ataxia, and seizure susceptibility in a model of a progressive myoclonus epilepsy.
Cell Rep Med
; 5(2): 101389, 2024 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266642
8.
Pharmacological modulation of Kv3 voltage-gated potassium channels regulates fear discrimination and expression in a response-dependent manner.
Prog Neuropsychopharmacol Biol Psychiatry
; 127: 110829, 2023 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37451593
9.
The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy.
Epilepsia
; 53(3): 412-24, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22220513
10.
The spectrum of anticonvulsant efficacy of retigabine (ezogabine) in animal models: implications for clinical use.
Epilepsia
; 53(3): 425-36, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22221318
11.
Kv3 Channels Contribute to the Excitability of Subpopulations of Spinal Cord Neurons in Lamina VII.
eNeuro
; 9(1)2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35058310
12.
The effects of AUT00206, a novel Kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia.
Psychopharmacology (Berl)
; 239(10): 3313-3323, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-36094619
13.
Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer's disease.
Brain Neurosci Adv
; 6: 23982128221086464, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35359460
14.
The effect of AUT00206, a Kv3 potassium channel modulator, on dopamine synthesis capacity and the reliability of [18F]-FDOPA imaging in schizophrenia.
J Psychopharmacol
; 36(9): 1061-1069, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-36164687
15.
The efficacy of sodium channel blockers to prevent phencyclidine-induced cognitive dysfunction in the rat: potential for novel treatments for schizophrenia.
J Pharmacol Exp Ther
; 338(1): 100-13, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21487071
16.
Using interleaved transcranial magnetic stimulation/functional magnetic resonance imaging (fMRI) and dynamic causal modeling to understand the discrete circuit specific changes of medications: lamotrigine and valproic acid changes in motor or prefrontal effective connectivity.
Psychiatry Res
; 194(2): 141-8, 2011 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21924874
17.
Sparsely Distributed, Pre-synaptic Kv3 K+ Channels Control Spontaneous Firing and Cross-Unit Synchrony via the Regulation of Synaptic Noise in an Auditory Brainstem Circuit.
Front Cell Neurosci
; 15: 721371, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34539351
18.
Effect of Kv3 channel modulators on auditory temporal resolution in aged Fischer 344 rats.
Hear Res
; 401: 108139, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33348192
19.
Potentiation of the anticonvulsant efficacy of sodium channel inhibitors by an NK1-receptor antagonist in the rat.
Epilepsia
; 51(8): 1543-51, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20067506
20.
Discovery of Vixotrigine: A Novel Use-Dependent Sodium Channel Blocker for the Treatment of Trigeminal Neuralgia.
ACS Med Chem Lett
; 11(9): 1678-1687, 2020 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32945812