Detalhe da pesquisa
1.
Fluorogenic structure activity library pinpoints molecular variations in substrate specificity of structurally homologous esterases.
J Biol Chem
; 293(36): 13851-13862, 2018 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30006352
2.
Microbial esterases and ester prodrugs: An unlikely marriage for combating antibiotic resistance.
Drug Dev Res
; 80(1): 33-47, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30302779
3.
Conformation-guided analogue design identifies potential antimalarial compounds through inhibition of mitochondrial respiration.
Org Biomol Chem
; 16(30): 5403-5406, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30009295
4.
In Vivo Delivery and Activation of Masked Fluorogenic Hydrolase Substrates by Endogenous Hydrolases in C.â elegans.
Chembiochem
; 18(18): 1807-1813, 2017 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28703362
5.
Ester-prodrugs of ethambutol control its antibacterial activity and provide rapid screening for mycobacterial hydrolase activity.
Bioorg Med Chem Lett
; 27(19): 4544-4547, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28882482
6.
Conformation-activity relationships of polyketide natural products.
Nat Prod Rep
; 32(8): 1183-206, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25974024
7.
Sequence and Structural Motifs Controlling the Broad Substrate Specificity of the Mycobacterial Hormone-Sensitive Lipase LipN.
ACS Omega
; 8(14): 13252-13264, 2023 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37065048
8.
Measuring the Global Substrate Specificity of Mycobacterial Serine Hydrolases Using a Library of Fluorogenic Ester Substrates.
ACS Infect Dis
; 4(6): 904-911, 2018 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29648787
9.
Conformational preferences of zampanolide and dactylolide.
Org Lett
; 15(20): 5246-9, 2013 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24102367
10.
High-throughput screen for small molecules that modulate the ATPase activity of the molecular chaperone DnaK.
Anal Biochem
; 372(2): 167-76, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17904512