Detalhe da pesquisa
1.
Chromatin signaling to kinetochores: transregulation of Dam1 methylation by histone H2B ubiquitination.
Cell
; 146(5): 709-19, 2011 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21884933
2.
Biosynthesis of the redox cofactor mycofactocin is controlled by the transcriptional regulator MftR and induced by long-chain acyl-CoA species.
J Biol Chem
; 298(1): 101474, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34896395
3.
Identification of a poly-cyclopropylglycine-containing peptide via bioinformatic mapping of radical S-adenosylmethionine enzymes.
J Biol Chem
; 298(5): 101881, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35367210
4.
New developments in RiPP discovery, enzymology and engineering.
Nat Prod Rep
; 38(1): 130-239, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32935693
5.
A two-component protease in Methylorubrum extorquens with high activity toward the peptide precursor of the redox cofactor pyrroloquinoline quinone.
J Biol Chem
; 294(41): 15025-15036, 2019 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31427437
6.
Pharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related Peptide.
J Pharmacol Exp Ther
; 374(1): 93-103, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32366601
7.
Spectroscopic and Electrochemical Characterization of the Mycofactocin Biosynthetic Protein, MftC, Provides Insight into Its Redox Flipping Mechanism.
Biochemistry
; 58(7): 940-950, 2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30628436
8.
MftD Catalyzes the Formation of a Biologically Active Redox Center in the Biosynthesis of the Ribosomally Synthesized and Post-translationally Modified Redox Cofactor Mycofactocin.
J Am Chem Soc
; 141(34): 13582-13591, 2019 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31381312
9.
Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway.
J Am Chem Soc
; 141(10): 4398-4405, 2019 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30811189
10.
Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase-Activating Peptide.
J Pharmacol Exp Ther
; 369(1): 26-36, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30643015
11.
Occurrence, function, and biosynthesis of mycofactocin.
Appl Microbiol Biotechnol
; 103(7): 2903-2912, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30778644
12.
Induction of Migraine-Like Photophobic Behavior in Mice by Both Peripheral and Central CGRP Mechanisms.
J Neurosci
; 37(1): 204-216, 2017 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28053042
13.
Mycofactocin Biosynthesis Proceeds through 3-Amino-5-[( p-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone (AHDP); Direct Observation of MftE Specificity toward MftA.
Biochemistry
; 57(37): 5379-5383, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30183269
14.
X-ray and EPR Characterization of the Auxiliary Fe-S Clusters in the Radical SAM Enzyme PqqE.
Biochemistry
; 57(8): 1306-1315, 2018 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29405700
15.
Mechanistic elucidation of the mycofactocin-biosynthetic radical S-adenosylmethionine protein, MftC.
J Biol Chem
; 292(31): 13022-13033, 2017 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28634235
16.
At the confluence of ribosomally synthesized peptide modification and radical S-adenosylmethionine (SAM) enzymology.
J Biol Chem
; 292(40): 16397-16405, 2017 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28830931
17.
Nuclear Magnetic Resonance Structure and Binding Studies of PqqD, a Chaperone Required in the Biosynthesis of the Bacterial Dehydrogenase Cofactor Pyrroloquinoline Quinone.
Biochemistry
; 56(21): 2735-2746, 2017 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28481092
18.
Demonstration That the Radical S-Adenosylmethionine (SAM) Enzyme PqqE Catalyzes de Novo Carbon-Carbon Cross-linking within a Peptide Substrate PqqA in the Presence of the Peptide Chaperone PqqD.
J Biol Chem
; 291(17): 8877-84, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26961875
19.
Catalytic Mechanism of the Hotdog-Fold Thioesterase PA1618 Revealed by X-ray Structure Determination of a Substrate-Bound Oxygen Ester Analogue Complex.
Chembiochem
; 18(19): 1935-1943, 2017 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28741300
20.
Crystal structures reveal metal-binding plasticity at the metallo-ß-lactamase active site of PqqB from Pseudomonas putida.
J Biol Inorg Chem
; 22(7): 1089-1097, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28825148