Detalhe da pesquisa
1.
Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis.
J Pharmacol Exp Ther
; 386(2): 242-258, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37308266
2.
Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice.
J Hepatol
; 61(1): 107-15, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24681344
3.
JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.
Sci Rep
; 13(1): 13524, 2023 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37598239
4.
Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor.
J Med Chem
; 65(21): 14721-14739, 2022 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36279149
5.
Author Correction: JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.
Sci Rep
; 13(1): 20081, 2023 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37973811
6.
Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress.
J Mol Med (Berl)
; 94(11): 1241-1253, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27394413
7.
Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis.
Nanomedicine (Lond)
; 10(17): 2697-708, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26020857
8.
Microparticles release by adipocytes act as "find-me" signals to promote macrophage migration.
PLoS One
; 10(4): e0123110, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25849214
9.
Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.
PLoS One
; 9(9): e107658, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25251155
10.
Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells.
Sci Signal
; 6(296): ra88, 2013 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24106341
11.
Analysis of genetic polymorphism 4a/b of the eNOS gene in infertile men: PS055.
Porto Biomed J
; 2(5): 199, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-32258668
12.
Prenatal androgen treatment alters body composition and glucose homeostasis in male rats.
J Endocrinol
; 208(3): 293-300, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21173020
13.
Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice.
J Clin Invest
; 121(2): 604-12, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21245576
14.
Transient prenatal androgen exposure produces metabolic syndrome in adult female rats.
Am J Physiol Endocrinol Metab
; 295(2): E262-8, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18544644