Detalhe da pesquisa
1.
Therapeutic Efficacy of 213Bi-labeled sdAbs in a Preclinical Model of Ovarian Cancer.
Mol Pharm
; 17(9): 3553-3566, 2020 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787284
2.
The Next-Generation Immune Checkpoint LAG-3 and Its Therapeutic Potential in Oncology: Third Time's a Charm.
Int J Mol Sci
; 22(1)2020 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33374804
3.
Scrutiny of chimeric antigen receptor activation by the extracellular domain: experience with single domain antibodies targeting multiple myeloma cells highlights the need for case-by-case optimization.
Front Immunol
; 15: 1389018, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38720898
4.
Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment.
J Nucl Med
; 64(5): 751-758, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37055223
5.
Phase I Study of [68Ga]Ga-Anti-CD206-sdAb for PET/CT Assessment of Protumorigenic Macrophage Presence in Solid Tumors (MMR Phase I).
J Nucl Med
; 64(9): 1378-1384, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37474271
6.
Targeted Radionuclide Therapy with Low and High-Dose Lutetium-177-Labeled Single Domain Antibodies Induces Distinct Immune Signatures in a Mouse Melanoma Model.
Mol Cancer Ther
; 21(7): 1136-1148, 2022 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35499391
7.
Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma.
Front Immunol
; 13: 799636, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35634329
8.
TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy.
Front Immunol
; 13: 811867, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35493461
9.
Emerging applications of nanobodies in cancer therapy.
Int Rev Cell Mol Biol
; 369: 143-199, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35777863
10.
Site-Specific Radiolabeling of a Human PD-L1 Nanobody via Maleimide-Cysteine Chemistry.
Pharmaceuticals (Basel)
; 14(6)2021 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34201323
11.
Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade.
J Nucl Med
; 62(11): 1638-1644, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33712537
12.
Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade.
Mol Ther Methods Clin Dev
; 22: 172-182, 2021 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34485603
13.
Anti-human PD-L1 Nanobody for Immuno-PET Imaging: Validation of a Conjugation Strategy for Clinical Translation.
Biomolecules
; 10(10)2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33003481
14.
Targeting Neuropilin-1 with Nanobodies Reduces Colorectal Carcinoma Development.
Cancers (Basel)
; 12(12)2020 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33266104
15.
Preclinical Targeted α- and ß--Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies.
Cancers (Basel)
; 12(4)2020 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32326199
16.
Theranostics in immuno-oncology using nanobody derivatives.
Theranostics
; 9(25): 7772-7791, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31695800
17.
Noninvasive Imaging of the Immune Checkpoint LAG-3 Using Nanobodies, from Development to Pre-Clinical Use.
Biomolecules
; 9(10)2019 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31569553
18.
Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production.
Vaccines (Basel)
; 7(3)2019 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31394834
19.
Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages.
J Control Release
; 299: 107-120, 2019 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30797866
20.
Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent.
Cancers (Basel)
; 11(6)2019 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31234464