Detalhe da pesquisa
1.
The hybrid RAVE complex plays V-ATPase-dependent and -independent pathobiological roles in Cryptococcus neoformans.
PLoS Pathog
; 19(10): e1011721, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37812645
2.
Discovery of N-benzylbenzamide-based allosteric inhibitors of Aurora kinase A.
Bioorg Med Chem
; 102: 117658, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460487
3.
Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase.
J Enzyme Inhib Med Chem
; 38(1): 2217695, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37246947
4.
Development of a Rapid LC-MS/MS Method for Simultaneous Quantification of Donepezil and Tadalafil in Rat Plasma: Its Application in a Pharmacokinetic Interaction Study after Oral Administration in Rats.
Molecules
; 28(5)2023 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36903595
5.
In vitro and in vivo neuroprotective effect of novel mPGES-1 inhibitor in animal model of Parkinson's disease.
Bioorg Med Chem Lett
; 74: 128920, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35931244
6.
Identification of highly selective type II kinase inhibitors with chiral peptidomimetic tails.
J Enzyme Inhib Med Chem
; 37(1): 1257-1277, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484863
7.
Dieckol Isolated from Eisenia bicyclis Ameliorates Wrinkling and Improves Skin Hydration via MAPK/AP-1 and TGF-ß/Smad Signaling Pathways in UVB-Irradiated Hairless Mice.
Mar Drugs
; 20(12)2022 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36547926
8.
Discovery of N-amido-phenylsulfonamide derivatives as novel microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors.
Bioorg Med Chem Lett
; 41: 127992, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33775835
9.
Design, synthesis and anti-inflammatory activity of imidazol-5-yl pyridine derivatives as p38α/MAPK14 inhibitor.
Bioorg Med Chem
; 31: 115969, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33422910
10.
Eisenia bicyclis Extract Repairs UVB-Induced Skin Photoaging In Vitro and In Vivo: Photoprotective Effects.
Mar Drugs
; 19(12)2021 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34940692
11.
Synthesis of Halogenated 1,5-Diarylimidazoles and Their Inhibitory Effects on LPS-Induced PGE2 Production in RAW 264.7 Cells.
Molecules
; 26(20)2021 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34684673
12.
Evaluation of the Inhibitory Effects of Pyridylpyrazole Derivatives on LPS-Induced PGE2 Productions and Nitric Oxide in Murine RAW 264.7 Macrophages.
Molecules
; 26(21)2021 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34770896
13.
A Pharmacokinetic Study of Ephedrine and Pseudoephedrine after Oral Administration of Ojeok-San by Validated LC-MS/MS Method in Human Plasma.
Molecules
; 26(22)2021 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34834083
14.
Inhibitory effects of triarylpyrazole derivatives on LPS-induced nitric oxide and PGE2 productions in murine RAW 264.7 macrophages.
Bioorg Med Chem Lett
; 30(4): 126884, 2020 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31879211
15.
Synthesis and cytotoxic effects of 2-thio-3,4-dihydroquinazoline derivatives as novel T-type calcium channel blockers.
Bioorg Med Chem
; 28(11): 115491, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32327350
16.
Diarylurea derivatives comprising 2,4-diarylpyrimidines: Discovery of novel potential anticancer agents via combined failed-ligands repurposing and molecular hybridization approaches.
Bioorg Chem
; 103: 104121, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32745753
17.
Quantitation of plasma and biliary cefpiramide concentrations in human samples using high-performance liquid chromatography.
Biomed Chromatogr
; 34(12): e4957, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32706918
18.
Isoflavones Isolated from the Seeds of Millettia ferruginea Induced Apoptotic Cell Death in Human Ovarian Cancer Cells.
Molecules
; 25(1)2020 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31947862
19.
Development and Validation of an LC-MS/MS Assay to Quantitate 2',4',6'-Trihydroxyacetophenone in Rat and Dog Plasma and its Application to a Pharmacokinetic Study.
Molecules
; 25(19)2020 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32977631
20.
A novel mPGES-1 inhibitor alleviates inflammatory responses by downregulating PGE2 in experimental models.
Prostaglandins Other Lipid Mediat
; 144: 106347, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31229523