Detalhe da pesquisa
1.
A rapid intracellular enrichment of alkylating payload is essential for melphalan flufenamide potency and mechanism of action.
Biochem Biophys Res Commun
; 656: 122-130, 2023 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37032581
2.
Prognostic significance of esterase gene expression in multiple myeloma.
Br J Cancer
; 124(8): 1428-1436, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33531688
3.
The Wittig bioconjugation of maleimide derived, water soluble phosphonium ylides to aldehyde-tagged proteins.
Org Biomol Chem
; 19(47): 10417-10423, 2021 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34817496
4.
Progress and Future Directions with Peptide-Drug Conjugates for Targeted Cancer Therapy.
Molecules
; 26(19)2021 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34641586
5.
Magnetic Beads for Desalting of Monoclonal Antibodies and Antibody-Drug Conjugates.
Anal Chem
; 92(13): 9001-9007, 2020 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32441508
6.
Azithromycin ameliorates sulfur dioxide-induced airway epithelial damage and inflammatory responses.
Respir Res
; 21(1): 233, 2020 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32912304
7.
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia.
Respir Res
; 20(1): 129, 2019 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31234850
8.
Application of triple quadrupole mass spectrometry for the characterization of antibody-drug conjugates.
Anal Bioanal Chem
; 411(12): 2569-2576, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30848315
9.
Qualitative analysis of antibody-drug conjugates (ADCs): an experimental comparison of analytical techniques of cysteine-linked ADCs.
Analyst
; 143(22): 5487-5496, 2018 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30289422
10.
Affibody-based hBCMA x CD16 dual engagers for NK cell-mediated killing of multiple myeloma cells.
N Biotechnol
; 77: 139-148, 2023 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37673373
11.
Potential Use of Supercharging Agents for Improved Mass Spectrometric Analysis of Monoclonal Antibodies and Antibody-Drug Conjugates.
J Am Soc Mass Spectrom
; 33(7): 1161-1167, 2022 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35704800
12.
Aminopeptidases in Cancer, Biology and Prospects for Pharmacological Intervention.
Curr Cancer Drug Targets
; 23(1): 25-46, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35747970
13.
Growth Response and Differentiation of Bone Marrow-Derived Mesenchymal Stem/Stromal Cells in the Presence of Novel Multiple Myeloma Drug Melflufen.
Cells
; 11(9)2022 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35563880
14.
The Peptide-Drug Conjugate Melflufen Modulates the Unfolded Protein Response of Multiple Myeloma and Amyloidogenic Plasma Cells and Induces Cell Death.
Hemasphere
; 6(3): e687, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35243210
15.
Novel Peptide-drug Conjugate Melflufen Efficiently Eradicates Bortezomib-resistant Multiple Myeloma Cells Including Tumor-initiating Myeloma Progenitor Cells.
Hemasphere
; 5(7): e602, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34136753
16.
Melphalan flufenamide inhibits osteoclastogenesis by suppressing proliferation of monocytes.
Bone Rep
; 15: 101098, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34150958
17.
Aminopeptidase Expression in Multiple Myeloma Associates with Disease Progression and Sensitivity to Melflufen.
Cancers (Basel)
; 13(7)2021 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33810334
18.
Optimization of isochromanone based urotensin II receptor agonists.
Bioorg Med Chem
; 18(13): 4844-54, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20570157
19.
Investigating the Impact of Sample Preparation on Mass Spectrometry-Based Drug-To-Antibody Ratio Determination for Cysteine- and Lysine-Linked Antibody-Drug Conjugates.
Antibodies (Basel)
; 9(3)2020 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911603
20.
Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing.
ChemMedChem
; 15(24): 2500-2512, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33063934