1.
Org Biomol Chem
; 13(3): 817-24, 2015 Jan 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25407091
RESUMO
Amides and ketones were intramolecularly coupled in the presence of KOt-Bu/DMF. The reaction provided good yields of a variety of isoquinolinones. A reaction mechanism of radical addition and subsequent E2-elimination is proposed.