Detalhe da pesquisa
1.
Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs.
Nature
; 494(7435): 105-10, 2013 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23354045
2.
The nuclear receptor PPARß/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2.
Genes Dev
; 25(24): 2619-30, 2011 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22135324
3.
The Failing Heart Relies on Ketone Bodies as a Fuel.
Circulation
; 133(8): 698-705, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26819376
4.
Skeletal muscle PGC-1ß signaling is sufficient to drive an endurance exercise phenotype and to counteract components of detraining in mice.
Am J Physiol Endocrinol Metab
; 312(5): E394-E406, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28270443
5.
Fueling Cardiac Hypertrophy.
Circ Res
; 126(2): 197-199, 2020 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31944916
6.
A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth.
Circ Res
; 114(4): 626-36, 2014 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24366168
7.
A role for peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1) in the regulation of cardiac mitochondrial phospholipid biosynthesis.
J Biol Chem
; 289(4): 2250-9, 2014 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24337569
8.
Sodium-glucose co-transporter 2 Inhibitors Act Independently of SGLT2 to Confer Benefit for Heart Failure with Reduced Ejection Fraction in Mice.
bioRxiv
; 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38746425
9.
RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure.
J Clin Invest
; 133(9)2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927960
10.
Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response.
J Biol Chem
; 286(13): 11155-62, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21321124
11.
Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha.
Circ Res
; 107(2): 233-41, 2010 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20522803
12.
Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.
Cell Metab
; 4(3): 199-210, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16950137
13.
Ubiquitin proteasome-dependent degradation of the transcriptional coactivator PGC-1{alpha} via the N-terminal pathway.
J Biol Chem
; 285(51): 40192-200, 2010 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20713359
14.
Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent in LDL receptor-null mice.
Nat Med
; 9(8): 1069-75, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12847522
15.
Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure.
Circ Heart Fail
; 14(1): e007684, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33356362
16.
Interaction between the UCP2 -866 G>A polymorphism, diabetes, and beta-blocker use among patients with acute coronary syndromes.
Pharmacogenet Genomics
; 20(4): 231-8, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20145583
17.
Impaired contractile function and calcium handling in hearts of cardiac-specific calcineurin b1-deficient mice.
Am J Physiol Heart Circ Physiol
; 297(4): H1263-73, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19700627
18.
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.
PLoS Biol
; 3(4): e101, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15760270
19.
The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus.
J Clin Invest
; 109(1): 121-30, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11781357
20.
Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization.
Circulation
; 112(15): 2339-46, 2005 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16203912