Detalhe da pesquisa
1.
THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1.
Nat Immunol
; 18(4): 433-441, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28250424
2.
Themis2 lowers the threshold for B cell activation during positive selection.
Nat Immunol
; 18(2): 205-213, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27992403
3.
THEMIS promotes T cell development and maintenance by rising the signaling threshold of the inhibitory receptor BTLA.
Proc Natl Acad Sci U S A
; 121(20): e2318773121, 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38713628
4.
Positive regulation of Vav1 by Themis controls CD4 T cell pathogenicity in a mouse model of central nervous system inflammation.
Cell Mol Life Sci
; 81(1): 161, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38565808
5.
Erratum: THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1.
Nat Immunol
; 18(6): 705, 2017 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28518157
6.
CD5 signalosome coordinates antagonist TCR signals to control the generation of Treg cells induced by foreign antigens.
Proc Natl Acad Sci U S A
; 117(23): 12969-12979, 2020 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32434911
7.
Themis, a T cell-specific protein important for late thymocyte development.
Nat Immunol
; 10(8): 840-7, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19597498
8.
THEMIS: Two Models, Different Thresholds.
Trends Immunol
; 38(9): 622-632, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28697966
9.
Grb2-Mediated Recruitment of USP9X to LAT Enhances Themis Stability following Thymic Selection.
J Immunol
; 199(8): 2758-2766, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28877990
10.
Proteomic Analysis of Regulatory T Cells Reveals the Importance of Themis1 in the Control of Their Suppressive Function.
Mol Cell Proteomics
; 16(8): 1416-1432, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28373295
11.
An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development.
J Immunol
; 195(4): 1608-16, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26163585
12.
Thpok-independent repression of Runx3 by Gata3 during CD4+ T-cell differentiation in the thymus.
Eur J Immunol
; 43(4): 918-28, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23310955
13.
Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function.
J Immunol
; 189(3): 1154-61, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22732588
14.
Negative times negative equals positive, THEMIS sets the rule on thymic selection and peripheral T cell responses.
Biomed J
; 45(2): 334-346, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35346866
15.
A selective LIS1 requirement for mitotic spindle assembly discriminates distinct T-cell division mechanisms within the T-cell lineage.
Elife
; 112022 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36519536
16.
THEMIS enhances the magnitude of normal and neuroinflammatory type 1 immune responses by promoting TCR-independent signals.
Sci Signal
; 15(742): eabl5343, 2022 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35857631
17.
Tyrosine phosphorylation controls nuclear localization and transcriptional activity of Ssdp1 in mammalian cells.
J Cell Biochem
; 103(6): 1856-65, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18080319
18.
Negative signaling in Fc receptor complexes.
Adv Immunol
; 89: 39-86, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16682272
19.
Regulatory mechanisms in T cell receptor signalling.
Nat Rev Immunol
; 18(8): 485-497, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29789755
20.
Themis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability.
Sci Signal
; 9(428): ra51, 2016 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27188442