Detalhe da pesquisa
1.
The putative RNA helicase DDX1 associates with the nuclear RNA exosome and modulates RNA/DNA hybrids (R-loops).
J Biol Chem
; 300(2): 105646, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38219817
2.
A budding yeast model for human disease mutations in the EXOSC2 cap subunit of the RNA exosome complex.
RNA
; 27(9): 1046-1067, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34162742
3.
A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons.
PLoS Genet
; 16(7): e1008901, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32645003
4.
An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14.
J Biol Chem
; 296: 100118, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33234594
5.
Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness.
Hum Mol Genet
; 29(13): 2218-2239, 2020 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504085
6.
The RNA exosome and RNA exosome-linked disease.
RNA
; 24(2): 127-142, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29093021
7.
Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer.
Nucleic Acids Res
; 46(9): 4515-4532, 2018 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29522130
8.
The RNA-binding protein, ZC3H14, is required for proper poly(A) tail length control, expression of synaptic proteins, and brain function in mice.
Hum Mol Genet
; 26(19): 3663-3681, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28666327
9.
A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly(A) tail length.
RNA
; 20(5): 681-8, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24671764
10.
Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans.
Proc Natl Acad Sci U S A
; 108(30): 12390-5, 2011 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21734151
11.
The RNA helicase DDX1 associates with the nuclear RNA exosome and modulates R-loops.
bioRxiv
; 2023 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37131662
12.
The Drosophila Nab2 RNA binding protein inhibits m6A methylation and male-specific splicing of Sex lethal transcript in female neuronal tissue.
Elife
; 122023 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37458420
13.
A Biallelic Variant of the RNA Exosome Gene EXOSC4 Causes Translational Defects Associated with a Neurodevelopmental Disorder.
medRxiv
; 2023 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961665
14.
Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex.
J Biol Chem
; 286(43): 37429-45, 2011 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21878619
15.
Loss of nuclear poly(A)-binding protein 1 causes defects in myogenesis and mRNA biogenesis.
Hum Mol Genet
; 19(6): 1058-65, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20035013
16.
Recognition of polyadenosine RNA by the zinc finger domain of nuclear poly(A) RNA-binding protein 2 (Nab2) is required for correct mRNA 3'-end formation.
J Biol Chem
; 285(34): 26022-32, 2010 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20554526
17.
The RNA Exosome and Human Disease.
Methods Mol Biol
; 2062: 3-33, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31768969
18.
The mating response cascade does not modulate changes in the steady-state level of target mRNAs through control of mRNA stability.
Yeast
; 26(5): 261-72, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19319831
19.
Insight into the RNA Exosome Complex Through Modeling Pontocerebellar Hypoplasia Type 1b Disease Mutations in Yeast.
Genetics
; 205(1): 221-237, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27777260
20.
The Conserved, Disease-Associated RNA Binding Protein dNab2 Interacts with the Fragile X Protein Ortholog in Drosophila Neurons.
Cell Rep
; 20(6): 1372-1384, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28793261