Detalhe da pesquisa
1.
A selective antibiotic for Lyme disease.
Cell
; 184(21): 5405-5418.e16, 2021 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34619078
2.
Nonadditive functional interactions between ligand-binding sites of the multidrug efflux pump AdeB from Acinetobacter baumannii.
J Bacteriol
; 206(1): e0021723, 2024 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37850798
3.
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics.
Antimicrob Agents Chemother
; 67(2): e0137722, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36715507
4.
Identification and structure-activity relationships for a series of N, N-disubstituted 2-aminobenzothiazoles as potent inhibitors of S. aureus.
Bioorg Med Chem Lett
; 89: 129301, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37094726
5.
The Whole Is Bigger than the Sum of Its Parts: Drug Transport in the Context of Two Membranes with Active Efflux.
Chem Rev
; 121(9): 5597-5631, 2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596653
6.
Inactivation of AdeABC and AdeIJK efflux pumps elicits specific nonoverlapping transcriptional and phenotypic responses in Acinetobacter baumannii.
Mol Microbiol
; 114(6): 1049-1065, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32858760
7.
Loss of RND-Type Multidrug Efflux Pumps Triggers Iron Starvation and Lipid A Modifications in Pseudomonas aeruginosa.
Antimicrob Agents Chemother
; 65(10): e0059221, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34252310
8.
Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria.
J Chem Inf Model
; 60(6): 2838-2847, 2020 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32453589
9.
First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors.
Bioorg Med Chem Lett
; 29(14): 1836-1841, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31104993
10.
Substrate Specificities and Efflux Efficiencies of RND Efflux Pumps of Acinetobacter baumannii.
J Bacteriol
; 200(13)2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29661860
11.
Erratum for Leus et al., "Substrate Specificities and Efflux Efficiencies of RND Efflux Pumps of Acinetobacter baumannii".
J Bacteriol
; 202(8)2020 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32217668
12.
Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors.
Commun Chem
; 7(1): 84, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38609430
13.
AdeIJK Pump-Specific Inhibitors Effective against Multidrug Resistant Acinetobacter baumannii.
ACS Infect Dis
; 10(6): 2239-2249, 2024 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38787939
14.
Acinetobacter baumannii Survival under Infection-Associated Stresses Depends on the Expression of Resistance-Nodulation-Division and Major Facilitator Superfamily Efflux Pumps.
Antibiotics (Basel)
; 13(1)2023 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38275317
15.
Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump.
mBio
; 14(4): e0140323, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37493633
16.
Making sense of drug-efflux transporters in the physiological environment.
Curr Opin Microbiol
; 69: 102179, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35882103
17.
Structure-Uptake Relationship Studies of Oxazolidinones in Gram-Negative ESKAPE Pathogens.
J Med Chem
; 65(20): 14144-14179, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36257060
18.
Property space mapping of Pseudomonas aeruginosa permeability to small molecules.
Sci Rep
; 12(1): 8220, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35581346
19.
Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates.
mBio
; 12(1)2021 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33622726
20.
A "Drug Sweeping" State of the TriABC Triclosan Efflux Pump from Pseudomonas aeruginosa.
Structure
; 29(3): 261-274.e6, 2021 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32966762