Pesquisa | BVS IEC

1.

Single-agent belantamab mafodotin in patients with relapsed/refractory multiple myeloma: Final analysis of the DREAMM-2 trial.

Nooka, Ajay K; Cohen, Adam D; Lee, Hans C; Badros, Ashraf; Suvannasankha, Attaya; Callander, Natalie; Abdallah, Al-Ola; Trudel, Suzanne; Chari, Ajai; Libby, Edward N; Chaudhry, Maria; Hultcrantz, Malin; Kortüm, K Martin; Popat, Rakesh; Sborov, Douglas; Hakim, Shawn; Lewis, Eric; Gorsh, Boris; Bhushan, Bharat; McKeown, Astrid; Gupta, Ira; Opalinska, Joanna; Richardson, Paul G; Lonial, Sagar.

Cancer ; 129(23): 3746-3760, 2023 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-37622738

2.

Phosphate Toxicity and Epithelial to Mesenchymal Transition.

Lewis, Eric; Seltun, Faith; Razzaque, Mohammed S; He, Ping.

Adv Exp Med Biol ; 1362: 73-84, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35288874

3.

Longer term outcomes with single-agent belantamab mafodotin in patients with relapsed or refractory multiple myeloma: 13-month follow-up from the pivotal DREAMM-2 study.

Lonial, Sagar; Lee, Hans C; Badros, Ashraf; Trudel, Suzanne; Nooka, Ajay K; Chari, Ajai; Abdallah, Al-Ola; Callander, Natalie; Sborov, Douglas; Suvannasankha, Attaya; Weisel, Katja; Voorhees, Peter M; Womersley, Lynsey; Baron, January; Piontek, Trisha; Lewis, Eric; Opalinska, Joanna; Gupta, Ira; Cohen, Adam D.

Cancer ; 127(22): 4198-4212, 2021 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-34314018

4.

Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM-2): a two-arm, randomised, open-label, phase 2 study.

Lonial, Sagar; Lee, Hans C; Badros, Ashraf; Trudel, Suzanne; Nooka, Ajay K; Chari, Ajai; Abdallah, Al-Ola; Callander, Natalie; Lendvai, Nikoletta; Sborov, Douglas; Suvannasankha, Attaya; Weisel, Katja; Karlin, Lionel; Libby, Edward; Arnulf, Bertrand; Facon, Thierry; Hulin, Cyrille; Kortüm, K Martin; Rodríguez-Otero, Paula; Usmani, Saad Z; Hari, Parameswaran; Baz, Rachid; Quach, Hang; Moreau, Philippe; Voorhees, Peter M; Gupta, Ira; Hoos, Axel; Zhi, Eric; Baron, January; Piontek, Trisha; Lewis, Eric; Jewell, Roxanne C; Dettman, Elisha J; Popat, Rakesh; Esposti, Simona Degli; Opalinska, Joanna; Richardson, Paul; Cohen, Adam D.

Lancet Oncol ; 21(2): 207-221, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31859245

5.

AIF promotes a JNK1-mediated cadherin switch independently of respiratory chain stabilization.

Scott, Andrew J; Walker, Sierra A; Krank, Joshua J; Wilkinson, Amanda S; Johnson, Kaitlyn M; Lewis, Eric M; Wilkinson, John C.

J Biol Chem ; 293(38): 14707-14722, 2018 09 21.

Artigo em Inglês | MEDLINE | ID: mdl-30093403

6.

Decoy.

Lewis, Eric.

Nature ; 554(7692): 398, 2018 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-32094733

7.

Fluidic Microactuation of Flexible Electrodes for Neural Recording.

Vitale, Flavia; Vercosa, Daniel G; Rodriguez, Alexander V; Pamulapati, Sushma Sri; Seibt, Frederik; Lewis, Eric; Yan, J Stephen; Badhiwala, Krishna; Adnan, Mohammed; Royer-Carfagni, Gianni; Beierlein, Michael; Kemere, Caleb; Pasquali, Matteo; Robinson, Jacob T.

Nano Lett ; 18(1): 326-335, 2018 01 10.

Artigo em Inglês | MEDLINE | ID: mdl-29220192

8.

Apoptosis Inducing Factor Binding Protein PGAM5 Triggers Mitophagic Cell Death That Is Inhibited by the Ubiquitin Ligase Activity of X-Linked Inhibitor of Apoptosis.

Lenhausen, Audrey M; Wilkinson, Amanda S; Lewis, Eric M; Dailey, Kaitlin M; Scott, Andrew J; Khan, Shahzeb; Wilkinson, John C.

Biochemistry ; 55(23): 3285-302, 2016 06 14.

Artigo em Inglês | MEDLINE | ID: mdl-27218139

9.

Differences in Host Innate Responses among Coccidioides Isolates in a Murine Model of Pulmonary Coccidioidomycosis.

Lewis, Eric R G; David, Victoria R; Doyle, Adina L; Rajabi, Khadijeh; Kiefer, Jeffrey A; Pirrotte, Patrick; Barker, Bridget M.

Eukaryot Cell ; 14(10): 1043-53, 2015 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-26275879

10.

Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models.

Shubitz, Lisa F; Trinh, Hien T; Galgiani, John N; Lewis, Maria L; Fothergill, Annette W; Wiederhold, Nathan P; Barker, Bridget M; Lewis, Eric R G; Doyle, Adina L; Hoekstra, William J; Schotzinger, Robert J; Garvey, Edward P.

Antimicrob Agents Chemother ; 59(12): 7249-54, 2015 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-26369964

11.

Fibronectin-binding protein of Borrelia hermsii expressed in the blood of mice with relapsing fever.

Lewis, Eric R G; Marcsisin, Renee A; Campeau Miller, Shelley A; Hue, Fong; Phillips, April; Aucoin, David P; Barbour, Alan G.

Infect Immun ; 82(6): 2520-31, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24686059

12.

The enzymatic activity of apoptosis-inducing factor supports energy metabolism benefiting the growth and invasiveness of advanced prostate cancer cells.

Lewis, Eric M; Wilkinson, Amanda S; Jackson, Jacqueline S; Mehra, Rohit; Varambally, Sooryanarayana; Chinnaiyan, Arul M; Wilkinson, John C.

J Biol Chem ; 287(52): 43862-75, 2012 Dec 21.

Artigo em Inglês | MEDLINE | ID: mdl-23118229

13.

Quantitative analysis of torsional stiffness in supplemental one-third tubular plate fixation in the management of isolated syndesmosis injuries: a biomechanical study.

Clanton, Thomas O; Matheny, Lauren M; Jarvis, Hannah C; Lewis, Eric V; Ambrose, Catherine G.

Foot Ankle Int ; 34(2): 267-72, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23413068

14.

Using integrated data to examine the effects of summer youth employment program completion on educational and criminal justice system outcomes: Evidence from Cuyahoga County, Ohio.

Atwell, Meghan Salas; Jeon, Jeesoo; Cho, Youngmin; Coulton, Claudia; Lewis, Eric; Sorensen, Alena.

Eval Program Plann ; 99: 102284, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37209641

15.

Dust devil: the life and times of the fungus that causes valley Fever.

Lewis, Eric R G; Bowers, Jolene R; Barker, Bridget M.

PLoS Pathog ; 11(5): e1004762, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25973899

16.

Nondegradative ubiquitination of apoptosis inducing factor (AIF) by X-linked inhibitor of apoptosis at a residue critical for AIF-mediated chromatin degradation.

Lewis, Eric M; Wilkinson, Amanda S; Davis, Nicole Y; Horita, David A; Wilkinson, John C.

Biochemistry ; 50(51): 11084-96, 2011 Dec 27.

Artigo em Inglês | MEDLINE | ID: mdl-22103349

17.

Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding.

Lewis, Eric M; Sergeant, Susan; Ledford, Bill; Stull, Natalie; Dinauer, Mary C; McPhail, Linda C.

J Biol Chem ; 285(5): 2959-67, 2010 Jan 29.

Artigo em Inglês | MEDLINE | ID: mdl-19948736

18.

Troponin measurements during drug development--considerations for monitoring and management of potential cardiotoxicity: an educational collaboration among the Cardiac Safety Research Consortium, the Duke Clinical Research Institute, and the US Food and Drug Administration.

Newby, L Kristin; Rodriguez, Ignacio; Finkle, John; Becker, Richard C; Hicks, Karen A; Hausner, Elizabeth; Chesler, Ruth; Harper, Courtney; Targum, Shari; Berridge, Brian R; Lewis, Eric; Walker, Dana B; Dollery, Colin; Turner, J Rick; Krucoff, Mitchell W.

Am Heart J ; 162(1): 64-73, 2011 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-21742091

19.

Effects of the HEET garment in the prevention of hypothermia in a porcine model.

Johnson, Don; Gegel, Brian; Burgert, James; Duncklee, Geoffrey W; Robison, Ricci R; Lewis, Eric J; Crum, Paul M; Kuhns, William; Moore, Daniel; O'Brien, Scott; Elliott, Joel; Washington, Jason; Boyle, John; Seigler, Dale.

J Surg Res ; 164(1): 126-30, 2010 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-20060130

20.

A Framework for Safety Evaluation Throughout the Product Development Life-Cycle.

Ball, Greg; Reblin, Tjark; Buchanan, James; Hendrickson, Barbara A; Lewis, Eric; Schnell, Patrick M; Rockhold, Frank W.

Ther Innov Regul Sci ; 54(4): 821-830, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-32557298

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Instituto Evandro Chagas

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