Detalhe da pesquisa
1.
Synthesis and biological evaluation of orally active anti-Trypanosoma agents.
Bioorg Med Chem
; 107: 117751, 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38762979
2.
RAP1 is essential for silencing telomeric variant surface glycoprotein genes in Trypanosoma brucei.
Cell
; 137(1): 99-109, 2009 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19345190
3.
POLIE suppresses telomerase-mediated telomere G-strand extension and helps ensure proper telomere C-strand synthesis in trypanosomes.
Nucleic Acids Res
; 50(4): 2036-2050, 2022 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35061898
4.
In vivo architecture of the telomerase RNA catalytic core in Trypanosoma brucei.
Nucleic Acids Res
; 49(21): 12445-12466, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34850114
5.
TbTRF suppresses the TERRA level and regulates the cell cycle-dependent TERRA foci number with a TERRA binding activity in its C-terminal Myb domain.
Nucleic Acids Res
; 49(10): 5637-5653, 2021 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34048580
6.
Synthesis and biological evaluation of imidamide analogs as selective anti-trypanosomal agents.
Bioorg Med Chem
; 61: 116740, 2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35396128
7.
Dynamics of rumen gene expression, microbiome colonization, and their interplay in goats.
BMC Genomics
; 22(1): 288, 2021 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33882826
8.
Pharmacokinetic study of an anti-trypanosome agent with different formulations and administration routes in mice by HPLC-MS/MS.
Biomed Chromatogr
; 35(10): e5169, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33978959
9.
Lead optimization of selective tubulin inhibitors as anti-trypanosomal agents.
Bioorg Med Chem
; 27(8): 1517-1528, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833159
10.
Trypanosoma brucei RAP1 maintains telomere and subtelomere integrity by suppressing TERRA and telomeric RNA:DNA hybrids.
Nucleic Acids Res
; 45(10): 5785-5796, 2017 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334836
11.
Effect of dietary concentrate to forage ratios on ruminal bacterial and anaerobic fungal populations of cashmere goats.
Anaerobe
; 59: 118-125, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31228671
12.
Synthesis and biological evaluation of selective tubulin inhibitors as anti-trypanosomal agents.
Bioorg Med Chem
; 25(12): 3215-3222, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28428042
13.
DNA double-strand breaks and telomeres play important roles in trypanosoma brucei antigenic variation.
Eukaryot Cell
; 14(3): 196-205, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25576484
14.
Suppression of subtelomeric VSG switching by Trypanosoma brucei TRF requires its TTAGGG repeat-binding activity.
Nucleic Acids Res
; 42(20): 12899-911, 2014 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25313155
15.
Silencing subtelomeric VSGs by Trypanosoma brucei RAP1 at the insect stage involves chromatin structure changes.
Nucleic Acids Res
; 41(16): 7673-82, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23804762
16.
Trypanosoma brucei Orc1 is essential for nuclear DNA replication and affects both VSG silencing and VSG switching.
Mol Microbiol
; 87(1): 196-210, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23216794
17.
Unwrap RAP1's Mystery at Kinetoplastid Telomeres.
Biomolecules
; 14(1)2024 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38254667
18.
Two Energetic Framework Materials Based on DNM-TNBI as Host Molecule: Effectively Coordinated by Different Cations.
Chem Asian J
; 19(9): e202301130, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38445562
19.
Folic Acid and Taurine Alleviate the Impairment of Redox Status, Immunity, Rumen Microbial Composition and Fermentation of Lambs under Heat Stress.
Animals (Basel)
; 14(7)2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38612237
20.
Uptake and detection rate of colorectal cancer screening with colonoscopy in China: A population-based, prospective cohort study.
Int J Nurs Stud
; 153: 104728, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38461798