Detalhe da pesquisa
1.
Luteolin, apigenin, and chrysin inhibit lipotoxicity-induced NLRP3 inflammasome activation and autophagy damage in macrophages by suppressing endoplasmic reticulum stress.
Environ Toxicol
; 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38654489
2.
Benzyl isothiocyanate attenuates activation of the NLRP3 inflammasome in Kupffer cells and improves diet-induced steatohepatitis.
Toxicol Appl Pharmacol
; 462: 116424, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36775252
3.
Andrographolide inhibits IL-1ß release in bone marrow-derived macrophages and monocyte infiltration in mouse knee joints induced by monosodium urate.
Toxicol Appl Pharmacol
; 410: 115341, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33242555
4.
Benzyl isothiocyanate ameliorates high-fat/cholesterol/cholic acid diet-induced nonalcoholic steatohepatitis through inhibiting cholesterol crystal-activated NLRP3 inflammasome in Kupffer cells.
Toxicol Appl Pharmacol
; 393: 114941, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32126212
5.
Andrographolide mitigates cardiac apoptosis to provide cardio-protection in high-fat-diet-induced obese mice.
Environ Toxicol
; 35(6): 707-713, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32023008
6.
14-Deoxy-11,12-didehydroandrographolide suppresses adipogenesis of 3 T3-L1 preadipocytes by inhibiting CCAAT/enhancer-binding protein ß activation and AMPK-mediated mitotic clonal expansion.
Toxicol Appl Pharmacol
; 359: 82-90, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30248417
7.
Andrographolide inhibits hypoxia-induced hypoxia-inducible factor 1α and endothelin 1 expression through the heme oxygenase 1/CO/cGMP/MKP-5 pathways in EA.hy926 cells.
Environ Toxicol
; 33(3): 269-279, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29165873
8.
Andrographolide inhibits hypoxia-induced HIF-1α-driven endothelin 1 secretion by activating Nrf2/HO-1 and promoting the expression of prolyl hydroxylases 2/3 in human endothelial cells.
Environ Toxicol
; 32(3): 918-930, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27297870
9.
Andrographolide inhibits adipogenesis of 3T3-L1 cells by suppressing C/EBPß expression and activation.
Toxicol Appl Pharmacol
; 307: 115-122, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27475717
10.
IP3 and calcium signaling involved in the reorganization of the actin cytoskeleton and cell rounding induced by cigarette smoke extract in human endothelial cells.
Environ Toxicol
; 31(11): 1293-1306, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25758670
11.
Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats.
Toxicol Appl Pharmacol
; 280(1): 1-9, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25110055
12.
Benzyl isothiocyanate inhibits TNFα-driven lipolysis via suppression of the ERK/PKA/HSL signaling pathway in 3T3-L1 adipocytes.
Nutr Res
; 121: 95-107, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38056034
13.
Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells.
Carcinogenesis
; 34(8): 1843-51, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23615401
14.
Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells.
Arch Toxicol
; 87(5): 857-69, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23288142
15.
Protection by chrysin, apigenin, and luteolin against oxidative stress is mediated by the Nrf2-dependent up-regulation of heme oxygenase 1 and glutamate cysteine ligase in rat primary hepatocytes.
Arch Toxicol
; 87(1): 167-78, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22864849
16.
Luteolin ameliorates palmitate-induced lipotoxicity in hepatocytes by mediating endoplasmic reticulum stress and autophagy.
Food Chem Toxicol
; 171: 113554, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36509263
17.
Andrographolide Attenuates Oxidized LDL-Induced Activation of the NLRP3 Inflammasome in Bone Marrow-Derived Macrophages and Mitigates HFCCD-Induced Atherosclerosis in Mice.
Am J Chin Med
; 51(8): 2175-2193, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37930331
18.
Andrographolide Inhibits Lipotoxicity-Induced Activation of the NLRP3 Inflammasome in Bone Marrow-Derived Macrophages.
Am J Chin Med
; 51(1): 129-147, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36419253
19.
Flavonoids protect pancreatic beta-cells from cytokines mediated apoptosis through the activation of PI3-kinase pathway.
Cytokine
; 59(1): 65-71, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22579112
20.
Inhibition of TNF-α-Induced Inflammation by andrographolide via down-regulation of the PI3K/Akt signaling pathway.
J Nat Prod
; 74(11): 2408-13, 2011 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22026410