Detalhe da pesquisa
1.
Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation.
J Am Chem Soc
; 146(12): 8536-8546, 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38480482
2.
Data Science-Enabled Palladium-Catalyzed Enantioselective Aryl-Carbonylation of Sulfonimidamides.
J Am Chem Soc
; 145(38): 20959-20967, 2023 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37656964
3.
Atroposelective Negishi Coupling Optimization Guided by Multivariate Linear Regression Analysis: Asymmetric Synthesis of KRAS G12C Covalent Inhibitor GDC-6036.
J Am Chem Soc
; 144(45): 20955-20963, 2022 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36326518
4.
Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma.
Bioorg Med Chem Lett
; 29(16): 2294-2301, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31307887
5.
Synthesis of Selective Estrogen Receptor Degrader GDC-0810 via Stereocontrolled Assembly of a Tetrasubstituted All-Carbon Olefin.
J Org Chem
; 83(19): 11571-11576, 2018 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30200756
6.
Highly Stereoselective Synthesis of Tetrasubstituted Acyclic All-Carbon Olefins via Enol Tosylation and Suzuki-Miyaura Coupling.
J Am Chem Soc
; 139(31): 10777-10783, 2017 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28715208
7.
Second-Generation Atroposelective Synthesis of KRAS G12C Covalent Inhibitor GDC-6036.
Org Lett
; 25(19): 3417-3422, 2023 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37162129
8.
Macrolactamization Approaches to Arylomycin Antibiotics Core.
Org Lett
; 21(1): 147-151, 2019 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30565949
9.
Stereocontrolled Synthesis of Arylomycin-Based Gram-Negative Antibiotic GDC-5338.
Org Lett
; 21(22): 9099-9103, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31668077
10.
Two-Step Synthesis of 3,4-Dihydropyrrolopyrazinones from Ketones and Piperazin-2-ones.
Org Lett
; 20(4): 1252-1255, 2018 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29406723
11.
Synthesis of a Selective Estrogen Receptor Degrader via a Stereospecific Elimination Approach.
Org Lett
; 20(4): 1114-1117, 2018 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29397753
12.
Synthesis of Highly Stereodefined Tetrasubstituted Acyclic All-Carbon Olefins via a Syn-Elimination Approach.
Org Lett
; 19(22): 6212-6215, 2017 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29115843
13.
Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARα Selective Agonist.
ACS Med Chem Lett
; 7(6): 590-4, 2016 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27326332
14.
Single-Step Synthesis of 5,6,7,8-Tetrahydroindolizines via Annulation of 2-Formylpiperidine and 1,3-Dicarbonyl Compounds.
Org Lett
; 17(14): 3564-7, 2015 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26132641
15.
One-pot synthesis of 4-substituted 3-amino-2-cyanothiophenes involving O-ethyl thioformate.
Org Lett
; 16(9): 2522-5, 2014 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24746285
16.
Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453).
J Med Chem
; 53(7): 2854-64, 2010 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20218621