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1.
Nano Lett ; 19(4): 2267-2271, 2019 04 10.
Artigo em Inglês | MEDLINE | ID: mdl-30897902

RESUMO

Three-dimensional (3D) single-particle tracking (SPT) is a key tool for studying dynamic processes in the life sciences. However, conventional optical elements utilizing light fields impose an inherent trade-off between lateral and axial resolution, preventing SPT with high spatiotemporal resolution across an extended volume. We overcome the typical loss in spatial resolution that accompanies light-field-based approaches to obtain 3D information by placing a standard microscope coverslip patterned with a multifunctional, light-field metasurface on a specimen. This approach enables an otherwise unmodified microscope to gather 3D information at an enhanced spatial resolution. We demonstrate simultaneous tracking of multiple fluorescent particles within a large 0.5 × 0.5 × 0.3 mm3 volume using a standard epi-fluorescent microscope with submicron lateral and micron-level axial resolution.

2.
Opt Express ; 26(19): 24835-24842, 2018 Sep 17.
Artigo em Inglês | MEDLINE | ID: mdl-30469594

RESUMO

Metasurface optical elements, optical phased arrays constructed from a dense arrangement of nanoscale antennas, are promising candidates for the next generation of flat optical components. Metasurfaces that rely on the Pancharatnam-Berry phase facilitate complete and efficient wavefront control. However, their operation typically requires control over the polarization state of the incident light to achieve a desired optical function. Here, we circumvent this inherent sensitivity to the incident polarization by multiplexing two metasurfaces that were designed to achieve the same optical function with incident light of opposite helicity. We analyze the optical performance of different multiplexing approaches, and demonstrate a subwavelength random interleaved polarization-independent metasurface lens operating in the visible spectrum, providing a diffraction-limited spot size for the shared-aperture.

3.
Nano Lett ; 16(12): 7671-7676, 2016 12 14.
Artigo em Inglês | MEDLINE | ID: mdl-27960478

RESUMO

Metasurfaces provide unprecedented control over light propagation by imparting local, space-variant phase changes on an incident electromagnetic wave. They can improve the performance of conventional optical elements and facilitate the creation of optical components with new functionalities and form factors. Here, we build on knowledge from shared aperture phased array antennas and Si-based gradient metasurfaces to realize various multifunctional metasurfaces capable of achieving multiple distinct functions within a single surface region. As a key point, we demonstrate that interleaving multiple optical elements can be accomplished without reducing the aperture of each subelement. Multifunctional optical elements constructed from Si-based gradient metasurface are realized, including axial and lateral multifocus geometric phase metasurface lenses. We further demonstrate multiwavelength color imaging with a high spatial resolution. Finally, optical imaging functionality with simultaneous color separation has been obtained by using multifunctional metasurfaces, which opens up new opportunities for the field of advanced imaging and display.

4.
Sci Rep ; 11(1): 15709, 2021 08 03.
Artigo em Inglês | MEDLINE | ID: mdl-34344965

RESUMO

Calcaneal quantitative ultrasonography (QUS) is a useful prescreening tool for osteoporosis, while the dual-energy X-ray absorptiometry (DXA) is the mainstream in clinical practice. We evaluated the correlation between QUS and DXA in a Taiwanese population. A total of 772 patients were enrolled and demographic data were recorded with the QUS and DXA T-score over the hip and spine. The correlation coefficient of QUS with the DXA-hip was 0.171. For DXA-spine, it was 0.135 overall, 0.237 in females, and 0.255 in males. The logistic regression model using DXA-spine as a dependent variable was established, and the classification table showed 66.2% accuracy. A receiver operating characteristic (ROC) analyses with Youden's Index revealed the optimal cut-off point of QUS for predicting osteoporosis to be 2.72. This study showed a meaningful correlation between QUS and DXA in a Taiwanese population. Thus, it is important to pre-screen for osteoporosis with calcaneus QUS.


Assuntos
Absorciometria de Fóton/métodos , Densidade Óssea , Calcâneo/diagnóstico por imagem , Osteoporose/diagnóstico por imagem , Ultrassonografia/métodos , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Modelos Logísticos , Masculino , Programas de Rastreamento , Pessoa de Meia-Idade , Prognóstico , Curva ROC , Sensibilidade e Especificidade , Taiwan
5.
Sci Rep ; 10(1): 20694, 2020 Nov 26.
Artigo em Inglês | MEDLINE | ID: mdl-33244040

RESUMO

There are few materials that are broadly used for fabricating optical metasurfaces for visible light applications. Gallium phosphide (GaP) is a material that, due to its optical properties, has the potential to become a primary choice but due to the difficulties in fabrication, GaP thin films deposited on transparent substrates have never been exploited. In this article we report the design, fabrication, and characterization of three different amorphous GaP metasurfaces obtained through sputtering. Although the material properties can be further optimized, our results show the potential of this material for visible applications making it a viable alternative in the material selection for optical metasurfaces.

6.
Nat Nanotechnol ; 13(12): 1191, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30443033

RESUMO

In the version of this Letter originally published, Zongfu Yu was mistakenly not noted as being a corresponding author; this has now been corrected in all versions of the Letter.

7.
Nat Nanotechnol ; 13(12): 1143-1147, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30374161

RESUMO

Sensing the direction of sounds gives animals clear evolutionary advantage. For large animals, with an ear-to-ear spacing that exceeds audible sound wavelengths, directional sensing is simply accomplished by recognizing the intensity and time differences of a wave impinging on its two ears1. Recent research suggests that in smaller, subwavelength animals, angle sensing can instead rely on a coherent coupling of soundwaves between the two ears2-4. Inspired by this natural design, here we show a subwarvelength photodetection pixel that can measure both the intensity and incident angle of light. It relies on an electrical isolation and optical coupling of two closely spaced Si nanowires that support optical Mie resonances5-7. When these resonators scatter light into the same free-space optical modes, a non-Hermitian coupling results that affords highly sensitive angle determination. By straightforward photocurrent measurements, we can independently quantify the stored optical energy in each nanowire and relate the difference in the stored energy between the wires to the incident angle of a light wave. We exploit this effect to fabricate a subwavelength angle-sensitive pixel with angular sensitivity, δθ = 0.32°.


Assuntos
Luz , Nanotecnologia/instrumentação , Nanofios/química , Dispositivos Ópticos , Silício/química , Animais , Biomimética , Desenho de Equipamento , Audição , Lagartos , Som
8.
Sci Rep ; 7(1): 2286, 2017 05 23.
Artigo em Inglês | MEDLINE | ID: mdl-28536465

RESUMO

Metasurfaces have facilitated the replacement of conventional optical elements with ultrathin and planar photonic structures. Previous designs of metasurfaces were limited to small deflection angles and small ranges of the angle of incidence. Here, we have created two types of Si-based metasurfaces to steer visible light to a large deflection angle. These structures exhibit high diffraction efficiencies over a broad range of angles of incidence. We have demonstrated metasurfaces working both in transmission and reflection modes based on conventional thin film silicon processes that are suitable for the large-scale fabrication of high-performance devices.

9.
Science ; 345(6194): 298-302, 2014 Jul 18.
Artigo em Inglês | MEDLINE | ID: mdl-25035488

RESUMO

Gradient metasurfaces are two-dimensional optical elements capable of manipulating light by imparting local, space-variant phase changes on an incident electromagnetic wave. These surfaces have thus far been constructed from nanometallic optical antennas, and high diffraction efficiencies have been limited to operation in reflection mode. We describe the experimental realization and operation of dielectric gradient metasurface optical elements capable of also achieving high efficiencies in transmission mode in the visible spectrum. Ultrathin gratings, lenses, and axicons have been realized by patterning a 100-nanometer-thick Si layer into a dense arrangement of Si nanobeam antennas. The use of semiconductors can broaden the general applicability of gradient metasurfaces, as they offer facile integration with electronics and can be realized by mature semiconductor fabrication technologies.

10.
Adv Mater ; 24(45): 6088-93, 2012 Nov 27.
Artigo em Inglês | MEDLINE | ID: mdl-22941856

RESUMO

By a reusable transfer fabrication technique, we demonstrate high-fidelity fabrication of metal nanoparticles, optical nanoantennas, and nanohole arrays directly on a functional silk biopolymer. The ability to reproducibly pattern silk biopolymers with arbitrarily complex plasmonic arrays is of importance for a variety of applications in optical biosensing, tissue engineering, cell biology, and the development of novel bio-optoelectronic medical devices.


Assuntos
Materiais Biocompatíveis/química , Técnicas Biossensoriais/métodos , Impressão Molecular/métodos , Seda/química , Seda/ultraestrutura , Ressonância de Plasmônio de Superfície/métodos , Teste de Materiais
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