Detalhe da pesquisa
1.
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
Cell
; 186(4): 786-802.e28, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36754049
2.
p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR).
Cell
; 184(3): 689-708.e20, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33482083
3.
Molecular Tweezers: Supramolecular Hosts with Broad-Spectrum Biological Applications.
Pharmacol Rev
; 75(2): 263-308, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36549866
4.
Overexpression of fibroblast growth factor-21 (FGF-21) protects mesenchymal stem cells against caspase-dependent apoptosis induced by oxidative stress and inflammation.
Cell Biol Int
; 44(10): 2163-2169, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32557962
5.
The mood stabilizer lithium potentiates the antidepressant-like effects and ameliorates oxidative stress induced by acute ketamine in a mouse model of stress.
Int J Neuropsychopharmacol
; 18(6)2014 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25548109
6.
Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD.
Neuron
; 111(9): 1381-1390.e6, 2023 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36931278
7.
SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS.
Cell Stem Cell
; 30(2): 171-187.e14, 2023 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36736291
8.
Role of diabetes- and obesity-related protein in the regulation of osteoblast differentiation.
Am J Physiol Endocrinol Metab
; 301(1): E40-8, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21467300
9.
Transplantation of Mesenchymal Stem Cells Overexpressing Fibroblast Growth Factor 21 Facilitates Cognitive Recovery and Enhances Neurogenesis in a Mouse Model of Traumatic Brain Injury.
J Neurotrauma
; 37(1): 14-26, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31298621
10.
Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons.
JCI Insight
; 52019 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31310593
11.
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
Nat Med
; 24(3): 313-325, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29400714
12.
Preconditioning mesenchymal stem cells with the mood stabilizers lithium and valproic acid enhances therapeutic efficacy in a mouse model of Huntington's disease.
Exp Neurol
; 281: 81-92, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27085395
13.
Preclinical and clinical investigations of mood stabilizers for Huntington's disease: what have we learned?
Int J Biol Sci
; 10(9): 1024-38, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25285035
14.
A new avenue for lithium: intervention in traumatic brain injury.
ACS Chem Neurosci
; 5(6): 422-33, 2014 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24697257
15.
Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation.
J Bone Miner Res
; 27(7): 1553-65, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22437732
16.
Glutaredoxin 5 regulates osteoblast apoptosis by protecting against oxidative stress.
Bone
; 44(5): 795-804, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19442627