Detalhe da pesquisa
1.
The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability.
Cell
; 185(12): 2035-2056.e33, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35688132
2.
Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity.
Cell
; 173(1): 62-73.e9, 2018 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29526462
3.
HSP90 Shapes the Consequences of Human Genetic Variation.
Cell
; 168(5): 856-866.e12, 2017 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215707
4.
A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance.
Cell
; 171(4): 966-979.e18, 2017 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29056345
5.
Intrinsically Disordered Proteins Drive Emergence and Inheritance of Biological Traits.
Cell
; 167(2): 369-381.e12, 2016 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27693355
6.
Sensitivity-enhanced NMR reveals alterations in protein structure by cellular milieus.
Cell
; 163(3): 620-8, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26456111
7.
Widespread macromolecular interaction perturbations in human genetic disorders.
Cell
; 161(3): 647-660, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25910212
8.
An evolutionarily conserved prion-like element converts wild fungi from metabolic specialists to generalists.
Cell
; 158(5): 1072-1082, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25171408
9.
The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy.
Cell
; 158(3): 564-78, 2014 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25083868
10.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
Cell
; 158(2): 434-448, 2014 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25036637
11.
Cross-kingdom chemical communication drives a heritable, mutually beneficial prion-based transformation of metabolism.
Cell
; 158(5): 1083-1093, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25171409
12.
Heritable remodeling of yeast multicellularity by an environmentally responsive prion.
Cell
; 153(1): 153-65, 2013 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23540696
13.
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.
Cell
; 150(5): 987-1001, 2012 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22939624
14.
HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers.
Cell
; 150(3): 549-62, 2012 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863008
15.
Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.
Mol Cell
; 73(5): 1001-1014.e8, 2019 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30527540
16.
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.
Cell
; 146(2): 318-31, 2011 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21757228
17.
A systematic survey identifies prions and illuminates sequence features of prionogenic proteins.
Cell
; 137(1): 146-58, 2009 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19345193
18.
α-Synuclein: membrane interactions and toxicity in Parkinson's disease.
Annu Rev Cell Dev Biol
; 26: 211-33, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20500090
19.
HSP90 at the hub of protein homeostasis: emerging mechanistic insights.
Nat Rev Mol Cell Biol
; 11(7): 515-28, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20531426
20.
Mitochondrial metabolism promotes adaptation to proteotoxic stress.
Nat Chem Biol
; 15(7): 681-689, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31133756