Detalhe da pesquisa
1.
The role of multidrug resistance protein (MRP-1) as an active efflux transporter on blood-brain barrier (BBB) permeability.
Mol Divers
; 21(2): 355-365, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28050687
2.
Determining the Exposure Threshold for Levonorgestrel Efficacy Using an Integrated Model Based Meta-Analysis Approach.
Clin Pharmacol Ther
; 111(2): 509-518, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34674227
3.
Development of a Translational Exposure-Bracketing Approach to Streamline the Development of Hormonal Contraceptive Drug Products.
Clin Pharmacol Ther
; 112(4): 909-916, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35723889
4.
Development of a model-based clinical trial simulation platform to optimize the design of clinical trials for Duchenne muscular dystrophy.
CPT Pharmacometrics Syst Pharmacol
; 11(3): 318-332, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34877803
5.
A randomized, cross-over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence.
Clin Transl Sci
; 15(7): 1764-1775, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35488487
6.
Development and Verification of a Body Weight-Directed Disease Trial Model for Glucose Homeostasis.
J Clin Pharmacol
; 61(2): 234-243, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32895980
7.
Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling.
CPT Pharmacometrics Syst Pharmacol
; 10(1): 48-58, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33217171
8.
Physiologically-based pharmacokinetics modeling to investigate formulation factors influencing the generic substitution of dabigatran etexilate.
CPT Pharmacometrics Syst Pharmacol
; 10(3): 199-210, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33449439
9.
Quantitative Benefit-Risk Assessment of P-gp-Mediated Drug-Drug Interactions of Dabigatran Coadministered With Pharmacokinetic Enhancers in Patients With Renal Impairment.
Clin Pharmacol Ther
; 109(1): 193-200, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33073366
10.
Predicting Cost-Effectiveness of Generic vs. Brand Dabigatran Using Pharmacometric Estimates Among Patients with Atrial Fibrillation in the United States.
Clin Transl Sci
; 13(2): 352-361, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32053288
11.
Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype-Derived Activity Scores.
CPT Pharmacometrics Syst Pharmacol
; 9(12): 678-685, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33067866
12.
Evaluating the Clinical Impact of Formulation Variability: A Metoprolol Extended-Release Case Study.
J Clin Pharmacol
; 59(9): 1266-1274, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31087554
13.
Classification of Breast Cancer Resistant Protein (BCRP) Inhibitors and Non-Inhibitors Using Machine Learning Approaches.
Comb Chem High Throughput Screen
; 18(5): 476-85, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26004050