Detalhe da pesquisa
1.
Preserved striatal innervation maintains motor function despite severe loss of nigral dopaminergic neurons.
Brain
; 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38574200
2.
The Potential of L-Type Calcium Channels as a Drug Target for Neuroprotective Therapy in Parkinson's Disease.
Annu Rev Pharmacol Toxicol
; 59: 263-289, 2019 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30625283
3.
Lower Affinity of Isradipine for L-Type Ca2+ Channels during Substantia Nigra Dopamine Neuron-Like Activity: Implications for Neuroprotection in Parkinson's Disease.
J Neurosci
; 37(28): 6761-6777, 2017 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28592699
4.
Increased dopamine D2 receptor activity in the striatum alters the firing pattern of dopamine neurons in the ventral tegmental area.
Proc Natl Acad Sci U S A
; 112(12): E1498-506, 2015 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25675529
5.
Ionic currents influencing spontaneous firing and pacemaker frequency in dopamine neurons of the ventrolateral periaqueductal gray and dorsal raphe nucleus (vlPAG/DRN): A voltage-clamp and computational modelling study.
J Comput Neurosci
; 42(3): 275-305, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28367595
6.
Converging roles of ion channels, calcium, metabolic stress, and activity pattern of Substantia nigra dopaminergic neurons in health and Parkinson's disease.
J Neurochem
; 139 Suppl 1: 156-178, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26865375
7.
Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization.
Ann Neurol
; 77(1): 15-32, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25363075
8.
How Parkinson's disease meets nucleolar stress.
Biochim Biophys Acta
; 1842(6): 791-7, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24412806
9.
Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons.
Brain
; 137(Pt 8): 2287-302, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24934288
10.
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase.
Nat Genet
; 38(10): 1184-91, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16964263
11.
Selective mitochondrial Ca2+ uptake deficit in disease endstage vulnerable motoneurons of the SOD1G93A mouse model of amyotrophic lateral sclerosis.
J Physiol
; 591(10): 2723-45, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23401612
12.
Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation.
Gastroenterology
; 142(5): 1229-1239.e3, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22342966
13.
Deep learning-based image analysis identifies a DAT-negative subpopulation of dopaminergic neurons in the lateral Substantia nigra.
Commun Biol
; 6(1): 1146, 2023 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37950046
14.
Control of sustained attention and impulsivity by Gq-protein signalling in parvalbumin interneurons of the anterior cingulate cortex.
Transl Psychiatry
; 13(1): 243, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37407615
15.
Telomere shortening reduces Alzheimer's disease amyloid pathology in mice.
Brain
; 134(Pt 7): 2044-56, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21672962
16.
ß2-subunit alternative splicing stabilizes Cav2.3 Ca2+ channel activity during continuous midbrain dopamine neuron-like activity.
Elife
; 112022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35792082
17.
Multi-Electrode Array Analysis Identifies Complex Dopamine Responses and Glucose Sensing Properties of Substantia Nigra Neurons in Mouse Brain Slices.
Front Synaptic Neurosci
; 13: 635050, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33716704
18.
Delayed-matching-to-position working memory in mice relies on NMDA-receptors in prefrontal pyramidal cells.
Sci Rep
; 11(1): 8788, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33888809
19.
Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress.
Antioxidants (Basel)
; 10(8)2021 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34439532
20.
Control of impulsivity by Gi-protein signalling in layer-5 pyramidal neurons of the anterior cingulate cortex.
Commun Biol
; 4(1): 662, 2021 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34079054