Detalhe da pesquisa
1.
Computationally guided AAV engineering for enhanced gene delivery.
Trends Biochem Sci
; 49(5): 457-469, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38531696
2.
On the sparsity of fitness functions and implications for learning.
Proc Natl Acad Sci U S A
; 119(1)2022 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34937698
3.
Conformal prediction under feedback covariate shift for biomolecular design.
Proc Natl Acad Sci U S A
; 119(43): e2204569119, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36256807
4.
Epigenome-wide association studies without the need for cell-type composition.
Nat Methods
; 11(3): 309-11, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24464286
5.
Greater power and computational efficiency for kernel-based association testing of sets of genetic variants.
Bioinformatics
; 30(22): 3206-14, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25075117
6.
Patterns of methylation heritability in a genome-wide analysis of four brain regions.
Nucleic Acids Res
; 41(4): 2095-104, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23303775
7.
FaST linear mixed models for genome-wide association studies.
Nat Methods
; 8(10): 833-5, 2011 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21892150
8.
A powerful and efficient set test for genetic markers that handles confounders.
Bioinformatics
; 29(12): 1526-33, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23599503
9.
Is Novelty Predictable?
Cold Spring Harb Perspect Biol
; 16(2)2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38052497
10.
Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy.
Sci Adv
; 10(4): eadj3786, 2024 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266077
11.
Widespread impact of HLA restriction on immune control and escape pathways of HIV-1.
J Virol
; 86(9): 5230-43, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22379086
12.
Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1.
J Virol
; 86(24): 13202-16, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23055555
13.
HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703.
J Immunol
; 186(10): 5675-86, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21498667
14.
Correction for hidden confounders in the genetic analysis of gene expression.
Proc Natl Acad Sci U S A
; 107(38): 16465-70, 2010 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20810919
15.
MBE: model-based enrichment estimation and prediction for differential sequencing data.
Genome Biol
; 24(1): 218, 2023 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37784130
16.
Coherent Blending of Biophysics-Based Knowledge with Bayesian Neural Networks for Robust Protein Property Prediction.
ACS Synth Biol
; 12(11): 3242-3251, 2023 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37888887
17.
Learning protein fitness models from evolutionary and assay-labeled data.
Nat Biotechnol
; 40(7): 1114-1122, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35039677
18.
Additive contribution of HLA class I alleles in the immune control of HIV-1 infection.
J Virol
; 84(19): 9879-88, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20660184
19.
Epistatic Net allows the sparse spectral regularization of deep neural networks for inferring fitness functions.
Nat Commun
; 12(1): 5225, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34471113
20.
Improved linear mixed models for genome-wide association studies.
Nat Methods
; 9(6): 525-6, 2012 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22669648