Pesquisa | BVS IEC

1.

Fibrotic immune microenvironment remodeling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma.

Liu, Xiaoyu; Zhou, Jingying; Wu, Haoran; Chen, Shufen; Zhang, Lingyun; Tang, Wenshu; Duan, Liang; Wang, Ying; McCabe, Eleanor; Hu, Mengying; Yu, Zhuo; Liu, Hanzhuang; Choi, Chung Hang Jonathan; Sung, Joseph Jao-Yiu; Huang, Leaf; Liu, Rihe; Cheng, Alfred Sze-Lok.

Mol Ther ; 31(1): 119-133, 2023 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-36146933

2.

Locally Trapping the C-C Chemokine Receptor Type 7 by Gene Delivery Nanoparticle Inhibits Lymphatic Metastasis Prior to Tumor Resection.

An, Sai; Tiruthani, Karthik; Wang, Ying; Xu, Ligeng; Hu, Mengying; Li, Jingjing; Song, Wantong; Jiang, Hongnan; Sun, Jirui; Liu, Rihe; Huang, Leaf.

Small ; 15(9): e1805182, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30690891

3.

LOVTRAP: an optogenetic system for photoinduced protein dissociation.

Wang, Hui; Vilela, Marco; Winkler, Andreas; Tarnawski, Miroslaw; Schlichting, Ilme; Yumerefendi, Hayretin; Kuhlman, Brian; Liu, Rihe; Danuser, Gaudenz; Hahn, Klaus M.

Nat Methods ; 13(9): 755-8, 2016 09.

Artigo em Inglês | MEDLINE | ID: mdl-27427858

4.

Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy.

Zhou, Jingying; Liu, Man; Sun, Hanyong; Feng, Yu; Xu, Liangliang; Chan, Anthony W H; Tong, Joanna H; Wong, John; Chong, Charing Ching Ning; Lai, Paul B S; Wang, Hector Kwong-Sang; Tsang, Shun-Wa; Goodwin, Tyler; Liu, Rihe; Huang, Leaf; Chen, Zhiwei; Sung, Joseph Jy; Chow, King Lau; To, Ka Fai; Cheng, Alfred Sze-Lok.

Gut ; 67(5): 931-944, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-28939663

5.

Discovery of small molecule inhibitors for the C. elegans caspase CED-3 by high-throughput screening.

Brantley, Scott J; Cotten, Steven W; Lamson, David R; Smith, Ginger R; Liu, Rihe; Williams, Kevin P.

Biochem Biophys Res Commun ; 491(3): 773-779, 2017 09 23.

Artigo em Inglês | MEDLINE | ID: mdl-28733033

6.

Targeted PRINT Hydrogels: The Role of Nanoparticle Size and Ligand Density on Cell Association, Biodistribution, and Tumor Accumulation.

Reuter, Kevin G; Perry, Jillian L; Kim, Dongwook; Luft, J Christopher; Liu, Rihe; DeSimone, Joseph M.

Nano Lett ; 15(10): 6371-8, 2015 Oct 14.

Artigo em Inglês | MEDLINE | ID: mdl-26389971

7.

In vitro selection of proteins with desired characteristics using mRNA-display.

Valencia, C Alexander; Zou, Jianwei; Liu, Rihe.

Methods ; 60(1): 55-69, 2013 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-23201412

8.

Universal STING mimic boosts antitumour immunity via preferential activation of tumour control signalling pathways.

Wang, Ying; Li, Sirui; Hu, Mengying; Yang, Yuchen; McCabe, Ellie; Zhang, Lillian; Withrow, Andrew M; Ting, Jenny P-Y; Liu, Rihe.

Nat Nanotechnol ; 19(6): 856-866, 2024 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-38480836

9.

Tribody: robust self-assembled trimeric targeting ligands with high stability and significantly improved target-binding strength.

Kim, Dongwook; Kim, Sang Kyun; Valencia, C Alexander; Liu, Rihe.

Biochemistry ; 52(41): 7283-94, 2013 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-24050811

10.

Ligand-installed polymeric nanocarriers for combination chemotherapy of EGFR-positive ovarian cancer.

Xi, Xinyuan; Lei, Fan; Gao, Keliang; Li, Jingjing; Liu, Rihe; Karpf, Adam R; Bronich, Tatiana K.

J Control Release ; 360: 872-887, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37478915

11.

Development of ¹⁸F-Labeled hydrophilic trans-cyclooctene as a bioorthogonal tool for PET probe construction.

Xu, Muyun; Ma, Xinrui; Pigga, Jessica E; Zhang, He; Wang, Shuli; Zhao, Weiling; Deng, Huaifu; Wu, Anna M; Liu, Rihe; Wu, Zhanhong; Fox, Joseph M; Li, Zibo.

Chem Commun (Camb) ; 59(97): 14387-14390, 2023 Dec 05.

Artigo em Inglês | MEDLINE | ID: mdl-37877355

12.

Unexpected multivalent display of proteins by temperature triggered self-assembly of elastin-like polypeptide block copolymers.

Hassouneh, Wafa; Fischer, Karl; MacEwan, Sarah R; Branscheid, Robert; Fu, Chuan Lawrence; Liu, Rihe; Schmidt, Manfred; Chilkoti, Ashutosh.

Biomacromolecules ; 13(5): 1598-605, 2012 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-22515311

13.

Nano-trapping CXCL13 reduces regulatory B cells in tumor microenvironment and inhibits tumor growth.

Shen, Limei; Li, Jingjing; Liu, Qi; Das, Manisit; Song, Wantong; Zhang, Xueqiong; Tiruthani, Karthik; Dorosheva, Oleksandra; Hu, Haiyang; Lai, Samuel K; Liu, Rihe; Huang, Leaf.

J Control Release ; 343: 303-313, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35104570

14.

Identification of a lacosamide binding protein using an affinity bait and chemical reporter strategy: 14-3-3 Î¶.

Park, Ki Duk; Kim, Dongwook; Reamtong, Onrapak; Eyers, Claire; Gaskell, Simon J; Liu, Rihe; Kohn, Harold.

J Am Chem Soc ; 133(29): 11320-30, 2011 Jul 27.

Artigo em Inglês | MEDLINE | ID: mdl-21692503

15.

Advantages of mRNA display selections over other selection techniques for investigation of protein-protein interactions.

Wang, Hui; Liu, Rihe.

Expert Rev Proteomics ; 8(3): 335-46, 2011 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-21679115

16.

mRNA Delivery of a Bispecific Single-Domain Antibody to Polarize Tumor-Associated Macrophages and Synergize Immunotherapy against Liver Malignancies.

Wang, Ying; Tiruthani, Karthik; Li, Sirui; Hu, Mengying; Zhong, Guojie; Tang, Yu; Roy, Sourav; Zhang, Lillian; Tan, Jun; Liao, Chengheng; Liu, Rihe.

Adv Mater ; 33(23): e2007603, 2021 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-33945178

17.

Tumor-targeted gene therapy with lipid nanoparticles inhibits tumor-associated adipocytes and remodels the immunosuppressive tumor microenvironment in triple-negative breast cancer.

Liu, Yun; Tiruthani, Karthik; Wang, Menglin; Zhou, Xuefei; Qiu, Nasha; Xiong, Yang; Pecot, Chad V; Liu, Rihe; Huang, Leaf.

Nanoscale Horiz ; 6(4): 319-329, 2021 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-33587080

18.

Proteomic searches comparing two (R)-lacosamide affinity baits: An electrophilic arylisothiocyanate and a photoactivated arylazide group.

Park, Ki Duk; Stables, James P; Liu, Rihe; Kohn, Harold.

Org Biomol Chem ; 8(12): 2803-13, 2010 Jun 21.

Artigo em Inglês | MEDLINE | ID: mdl-20405068

19.

Tumor neoantigen heterogeneity impacts bystander immune inhibition of pancreatic cancer growth.

Das, Manisit; Zhou, Xuefei; Liu, Yun; Das, Anirban; Vincent, Benjamin G; Li, Jingjing; Liu, Rihe; Huang, Leaf.

Transl Oncol ; 13(12): 100856, 2020 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-32862105

20.

In vitro protein selection.

Liu, Rihe.

Methods ; 60(1): 1-2, 2013 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-23651871

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