Detalhe da pesquisa
1.
Cellular processing of α-synuclein fibrils results in distinct physiological C-terminal truncations with a major cleavage site at residue Glu 114.
J Biol Chem
; 299(7): 104912, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37307916
2.
Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice.
Acta Neuropathol
; 143(6): 663-685, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35488930
3.
Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease.
J Neurosci
; 40(39): 7559-7576, 2020 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32868457
4.
Precision therapeutic targets for COVID-19.
Virol J
; 18(1): 66, 2021 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33781287
5.
A multiverse of α-synuclein: investigation of prion strain properties with carboxyl-terminal truncation specific antibodies in animal models.
Acta Neuropathol Commun
; 12(1): 91, 2024 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38858742
6.
Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis.
Acta Neuropathol Commun
; 11(1): 119, 2023 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37482615
7.
Proteinopathies and Neurotrauma: Update on Degenerative Cascades.
JSM Neurosurg Spine
; 9(1)2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36466377
8.
Targeted proteolytic products of τ and α-synuclein in neurodegeneration.
Essays Biochem
; 65(7): 905-912, 2021 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34846537
9.
Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies.
Acta Neuropathol Commun
; 9(1): 146, 2021 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34454615
10.
Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy.
Acta Neuropathol Commun
; 9(1): 80, 2021 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33941284
11.
Collusion of α-Synuclein and Aß aggravating co-morbidities in a novel prion-type mouse model.
Mol Neurodegener
; 16(1): 63, 2021 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503546
12.
Novel monoclonal antibodies targeting the RRM2 domain of human TDP-43 protein.
Neurosci Lett
; 738: 135353, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32905837
13.
Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier - phenotypic variability in autosomal dominant Alzheimer's disease.
Acta Neuropathol Commun
; 8(1): 31, 2020 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32164763
14.
Correction: Collusion of α-Synuclein and Aß aggravating co-morbidities in a novel prion-type mouse model.
Mol Neurodegener
; 19(1): 17, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38365847