RESUMO
Eighty hepatic artery Doppler ultrasound (US) examinations performed in 49 patients after liver transplantation were retrospectively analyzed to determine if loss of diastolic flow correlated with pathologic evidence of acute allograft rejection. All 80 Doppler examinations were performed within 7 days of hepatic needle biopsy. Forty-three Doppler waveforms from 27 patients showed normal diastolic flow. Seventeen Doppler studies in 17 patients showed complete absence of diastolic flow. Review of biopsy results for each group showed no significant difference in the proportion of acute allograft rejection present (42% for the normal group and 46% for the group lacking diastolic flow). The data from 53 US and biopsy examinations performed 2 days apart in 37 patients confirmed the lack of correlation between absent hepatic artery diastolic blood flow and rejection. The authors conclude that the loss of hepatic artery diastolic flow has no apparent clinical application for the diagnosis of acute hepatic allograft rejection.
Assuntos
Rejeição de Enxerto , Artéria Hepática/fisiologia , Transplante de Fígado , Ultrassonografia , Adulto , Biópsia , Velocidade do Fluxo Sanguíneo , Feminino , Humanos , Fígado/patologia , Circulação Hepática , Masculino , Pessoa de Meia-Idade , UltrassomRESUMO
Imaging of the renal, hepatic, and pancreas allograft is essential for evaluation of postoperative complications. Surgical complications after organ transplantation can generally be specifically diagnosed. These complications include obstruction, leakage, peritransplant fluid collections, and vascular problems such as vascular stenosis or thrombosis, arteriovenous fistula, and pseudoaneurysm. Using computed tomography (CT) or ultrasound guidance, interventional procedures can often be performed to treat various surgical complications. On the other hand, medical causes of allograft transplant dysfunction such as rejection, acute tubular necrosis, drug toxicity, ischemia, infection, inflammation, or the development of recurrent disease are frequently associated with nonspecific imaging findings. Allograft biopsy is still usually necessary for definitive diagnosis in these cases. In this article, we will briefly outline the spectrum of abnormalities that can be seen in the allograft recipient and show some examples of these complications.
Assuntos
Transplante de Rim/efeitos adversos , Transplante de Fígado/efeitos adversos , Transplante de Pâncreas/efeitos adversos , Complicações Pós-Operatórias/diagnóstico por imagem , Adolescente , Adulto , Criança , Feminino , Humanos , Transplante de Rim/diagnóstico por imagem , Transplante de Fígado/diagnóstico por imagem , Masculino , Transplante de Pâncreas/diagnóstico por imagem , Tomografia Computadorizada por Raios X , UltrassonografiaRESUMO
The assessment of the vasculature of the transplant recipient is complex; current emphasis is on utilization of noninvasive techniques, particularly conventional and color duplex sonography. These examinations reduce the need for diagnostic angiography, and their findings provide crucial information with regard to vascular complications seen after transplantation, such as arterial or venous stenosis or occlusion, arteriovenous fistulas, and pseudoaneurysms. However, the complexity of the clinical settings of these vascular complications often makes other noninvasive examinations, as well as angiography, necessary. Some complications are common to all three types of transplantations, but some, such as graft thrombosis in pancreatic transplantation, predominate in one particular type of transplant. Use of imaging is also important in identifying candidates for liver transplantation. In addition, access for therapeutic radiologic intervention can be provided with diagnostic angiographic procedures.
Assuntos
Transplante de Rim/efeitos adversos , Transplante de Fígado/efeitos adversos , Transplante de Pâncreas/efeitos adversos , Doenças Vasculares/diagnóstico , Humanos , Doenças Vasculares/etiologiaRESUMO
Color Doppler sonography is a useful technique for rapid, noninvasive evaluation of venous disease in the upper extremity. It has been used successfully to evaluate thrombosis related to indwelling central catheters. In addition, Doppler sonography shows promise for monitoring thrombolytic therapy after "effort thrombosis" and detecting intermittent venous compression related to thoracic outlet syndrome.
Assuntos
Braço/irrigação sanguínea , Veias Jugulares/diagnóstico por imagem , Síndrome do Desfiladeiro Torácico/diagnóstico por imagem , Trombose/diagnóstico por imagem , Ultrassonografia/métodos , Cateterismo Venoso Central/efeitos adversos , Humanos , Pescoço/irrigação sanguínea , Trombose/etiologia , UltrassomRESUMO
Surgically constructed Brescia-Cimino arteriovenous fistulas and synthetic loop grafts are common means of vascular access for hemodialysis. Although angiography has been the traditional method of imaging these vascular systems, duplex and color Doppler sonography offer a noninvasive method of evaluating dysfunctional hemodialysis access. In normally functioning fistulas, waveforms of flow in the supply arteries and throughout the graft are monophasic, with peak systolic velocities of 100-400 cm/sec and end-diastolic velocities of 60-200 cm/sec. The draining veins have arterial pulsations with peak velocities of 30-100 cm/sec. Arterial and venous stenoses, graft thrombosis (occlusive and nonocclusive), infection, aneurysm and pseudoaneurysm formation, and arterial steal are relatively common abnormalities that can threaten or destroy graft function and can be diagnosed sonographically. Although abnormal hemodynamics in access fistulas are usually detected during hemodialysis, sonographic evaluation at the time of initial dysfunction may reveal an underlying correctable abnormality, and specific therapy may be instituted before the condition progresses. In addition, use of sonography may obviate an invasive angiographic examination if no significant hemodynamic problem is present.
Assuntos
Derivação Arteriovenosa Cirúrgica , Prótese Vascular , Oclusão de Enxerto Vascular/diagnóstico por imagem , Diálise Renal , Antebraço/irrigação sanguínea , Humanos , Politetrafluoretileno , Artéria Radial/cirurgia , Ultrassom , Ultrassonografia/métodosRESUMO
Duplex and color Doppler sonography have proved to be excellent noninvasive modalities for evaluating complications of percutaneous interventional vascular procedures. Complications including hematoma, pseudoaneurysm, arteriovenous fistula, thrombosis, stenosis, and vessel occlusion are routinely diagnosed with Doppler sonography. Hematomas exhibit variable echogenicity and internal complexity but never demonstrate internal blood flow. A pseudoaneurysm is a contained extravasation of blood that, unlike a hematoma, maintains a patent vascular connection with the injured vessel. Puncture-related arteriovenous fistulas are false vascular channels between an adjacent artery and vein that demonstrate low-resistance arterial signal, high-velocity venous outflow, and variable flow patterns within themselves. Narrowing in a stent demonstrates high-velocity turbulent flow with conventional Doppler and color aliasing with color Doppler techniques. Thrombus can be seen directly as a mural-based or luminal defect; however, it is often alterations in color flow dynamics, waveform characteristics, and flow velocities that permit conclusive diagnosis. Early experience in evaluation of stent stenosis in patients with transjugular intrahepatic portosystemic shunts suggests that low-velocity shunt flow indicates stenosis, likely related to the presence of low-resistance collateral pathways. Familiarity with both the interventional procedures and their possible complications facilitates prompt diagnosis and treatment.
Assuntos
Doenças Vasculares/diagnóstico por imagem , Doenças Vasculares/etiologia , Aneurisma/diagnóstico por imagem , Angioplastia com Balão/efeitos adversos , Fístula Arteriovenosa/diagnóstico por imagem , Hematoma/diagnóstico por imagem , Humanos , Derivação Portossistêmica Cirúrgica/efeitos adversos , Punções/efeitos adversos , Stents/efeitos adversos , Trombose/diagnóstico por imagem , UltrassonografiaRESUMO
PURPOSE: The upper extremity veins of 17 patients who underwent operative central venous catheter placement were studied prospectively with color duplex sonography to determine which duplex changes, if any, could be due to the presence of the catheter alone and to determine if these waveform changes could mimic the dampened waveform seen peripheral to central nonvisualized or nonocclusive thrombosis or proximal stenosis. PATIENTS AND METHODS: The subclavian, internal jugular, and brachiocephalic veins were examined with color duplex sonography immediately before and after catheter placement. Images obtained before and after catheterization were reviewed by two radiologists for (a) spectral broadening in both the vein of insertion and the brachiocephalic vein, (b) transmission of atrial pulsations, and (c) respiratory phasicity. RESULTS: In all cases, atrial pulsatility and respiratory phasicity were present before and after catheter placement. There was no statistically significant change in the amount of spectral broadening after catheter placement. A mild increase in the peak blood flow velocity of 7 cm/sec (P = .04) in the ipsilateral brachiocephalic vein was demonstrated; however, no significant increase in velocity could be shown in the vein of insertion. CONCLUSION: In this clinical setting, the hemodynamic changes within the vein from the catheter placement are minimal. Any damping of the venous waveform seen with sonography performed to rule out upper extremity deep venous thrombosis secondary to indwelling catheter--for example, loss of atrial pulsatility or respiratory phasicity--is presumably due to the presence of venous thrombosis or stenosis.
Assuntos
Braço/irrigação sanguínea , Cateterismo Venoso Central , Veias/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Velocidade do Fluxo Sanguíneo , Veias Braquiocefálicas/diagnóstico por imagem , Constrição Patológica/diagnóstico por imagem , Diagnóstico Diferencial , Feminino , Humanos , Veias Jugulares/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Veia Subclávia/diagnóstico por imagem , Trombose/diagnóstico por imagem , UltrassonografiaRESUMO
Leakage from the urinary bladder or duodenal stump after pancreas transplantation with urinary bladder drainage of the graft is difficult to diagnose clinically. We retrospectively reviewed our experience with fluoroscopic cystography and CT to determine their relative merit in the diagnosis of pancreatic fluid and urine leakage as documented by surgical exploration in pancreas transplant recipients. Thirteen leaks were diagnosed by fluoroscopic cystography or by CT in 11 patients after pancreas transplantation with urinary bladder drainage of pancreatic fluid. Conventional retrograde fluoroscopic cystography showed 11 leaks; CT with retrograde bladder opacification showed three leaks. Of the five CT studies that did not show a leak and that also were done within 7 days of a cystogram with abnormal findings, failure to use retrograde bladder opacification accounted for the majority (three cases) of missed diagnoses. Focal or free peritoneal abdominal fluid was seen in all CT examinations, with extravasation of contrast material seen into both walled-off collections and free ascites. Our experience suggests that retrograde bladder and duodenal stump opacification should be a routine part of the CT evaluation performed to detect leakage from the urinary bladder or duodenal stump after pancreas transplantation.
Assuntos
Drenagem/métodos , Transplante de Pâncreas/efeitos adversos , Suco Pancreático , Complicações Pós-Operatórias/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Bexiga Urinária/diagnóstico por imagem , Urina , Anastomose Cirúrgica , Duodeno/cirurgia , Fluoroscopia/métodos , Humanos , Estudos Retrospectivos , Bexiga Urinária/cirurgiaRESUMO
Duplex sonography has established utility in the noninvasive evaluation of the portal venous system. Recently, the duplex sonographic features of suspected portal venous air have been described. We report on an experimental study in dogs undertaken to establish if the same sonographic features could be reproduced in a laboratory setting and to determine if small fragments of clot emboli could produce similar gray-scale and Doppler findings. Injections of microbubbles of air and clot fragments into the portal venous system were monitored using duplex ultrasound. The gray-scale and Doppler features of flow in the main portal vein were indistinguishable in both microbubble and clot injections. Superimposition of high-amplitude spikes on the normal portal venous waveform was seen in 19 of 24 (79%) microbubble and 13 of 23 (56%) clot fragment injections. We conclude that the appearance of rapidly moving, bright intraluminal echoes coupled with spike-like aberrations of the portal venous waveform can be associated with portal venous air bubbles or small blood clot emboli.
Assuntos
Embolia Aérea/diagnóstico por imagem , Veia Porta/diagnóstico por imagem , Trombose/diagnóstico por imagem , Animais , Cães , Ultrassom , Ultrassonografia/métodosRESUMO
Changes in flow in the subclavian artery and vein resulting from the use of a hyperabduction maneuver during Doppler sonography in 20 volunteers were compared with retrospective findings in 16 patients clinically suspected of having thoracic outlet syndrome. Significant compression of the subclavian artery showed in the Doppler waveform as at least a doubling of peak systolic velocity or complete cessation of flow with hyperabduction; significant compression of the subclavian vein was diagnosed by complete cessation of blood flow or loss of atrial and respiratory dynamics in the waveform of the subclavian vein with hyperabduction. In volunteers, asymptomatic compression of the subclavian vein with arm abduction was seen in two (10%) and asymptomatic compression of the subclavian artery was seen in four (20%). Of the 16 patients, thrombosis of the subclavian vein was found in seven, compression of the subclavian vein with hyperabduction was found in six, and diagnoses other than thoracic outlet syndrome were established as the cause of pain in three. When duplex sonography was compared with venography, which was performed in 10 patients, one false-negative case was found because a subclavian vein thrombus had not been detected. The subclavian artery was examined in five of the six patients with positional compression of the subclavian vein; compression of the subclavian artery was found in three. The clinical significance of compression of the subclavian artery cannot be determined from our data because of the small number of patients involved. When the sonographic criteria of subclavian vein clot or compression resulting in a complete loss of normal venous phasicity with arm abduction and the clinical criterion of subsequent improvement in symptoms after curative surgery are used, color Doppler sonography is 92% sensitive and 95% specific for the diagnosis of thoracic outlet syndrome. This preliminary study shows that Doppler sonography has potential in the evaluation of thoracic outlet syndrome.