Detalhe da pesquisa
1.
Dual regulation of hEAG1 channels by phosphatidylinositol 4,5-bisphosphate.
Biochem Biophys Res Commun
; 503(4): 2531-2535, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30208521
2.
The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization.
Am J Physiol Heart Circ Physiol
; 306(5): H747-54, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24375641
3.
A near-infrared fluorescent voltage-sensitive dye allows for moderate-throughput electrophysiological analyses of human induced pluripotent stem cell-derived cardiomyocytes.
Am J Physiol Heart Circ Physiol
; 307(9): H1370-7, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25172899
4.
Flecainide increases Kir2.1 currents by interacting with cysteine 311, decreasing the polyamine-induced rectification.
Proc Natl Acad Sci U S A
; 107(35): 15631-6, 2010 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-20713726
5.
Molecular mechanisms of chloroquine inhibition of heterologously expressed Kir6.2/SUR2A channels.
Mol Pharmacol
; 82(5): 803-13, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22851715
6.
Mechanisms for Kir channel inhibition by quinacrine: acute pore block of Kir2.x channels and interference in PIP2 interaction with Kir2.x and Kir6.2 channels.
Pflugers Arch
; 462(4): 505-17, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21779761
7.
Specific residues of the cytoplasmic domains of cardiac inward rectifier potassium channels are effective antifibrillatory targets.
FASEB J
; 24(11): 4302-12, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20585026
8.
The antimalarial drug mefloquine inhibits cardiac inward rectifier K+ channels: evidence for interference in PIP2-channel interaction.
J Cardiovasc Pharmacol
; 57(4): 407-15, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21502926
9.
The history and geographic distribution of a KCNQ1 atrial fibrillation risk allele.
Nat Commun
; 12(1): 6442, 2021 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34750360
10.
Tamoxifen inhibits cardiac ATP-sensitive and acetylcholine-activated K+ currents in part by interfering with phosphatidylinositol 4,5-bisphosphate-channel interaction.
J Pharmacol Sci
; 113(1): 66-75, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20472984
11.
Chloroquine blocks a mutant Kir2.1 channel responsible for short QT syndrome and normalizes repolarization properties in silico.
Cell Physiol Biochem
; 24(3-4): 153-60, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19710529
12.
Tamoxifen inhibits inward rectifier K+ 2.x family of inward rectifier channels by interfering with phosphatidylinositol 4,5-bisphosphate-channel interactions.
J Pharmacol Exp Ther
; 331(2): 563-73, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19654266
13.
ABCC9 is a novel Brugada and early repolarization syndrome susceptibility gene.
Int J Cardiol
; 171(3): 431-42, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24439875
14.
Structural bases for the different anti-fibrillatory effects of chloroquine and quinidine.
Cardiovasc Res
; 89(4): 862-9, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21233253
15.
Carvedilol inhibits Kir2.3 channels by interference with PIP2-channel interaction.
Eur J Pharmacol
; 668(1-2): 72-7, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21663737
16.
Thiopental inhibits function of different inward rectifying potassium channel isoforms by a similar mechanism.
Eur J Pharmacol
; 638(1-3): 33-41, 2010 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20447386