Detalhe da pesquisa
1.
Cryptosporidium life cycle small molecule probing implicates translational repression and an Apetala 2 transcription factor in macrogamont differentiation.
PLoS Pathog
; 20(4): e1011906, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38669269
2.
Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis.
PLoS Pathog
; 18(2): e1009862, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35134095
3.
Synthesis and structure-activity relationships of aryl fluorosulfate-based inhibitors as novel antitubercular agents.
Bioorg Med Chem Lett
; 98: 129596, 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38142914
4.
Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition.
Bioorg Med Chem Lett
; 90: 129328, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37196868
5.
Repurposing the Kinase Inhibitor Mavelertinib for Giardiasis Therapy.
Antimicrob Agents Chemother
; 66(7): e0001722, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35703552
6.
Pharmacokinetics and Pharmacodynamics of Clofazimine for Treatment of Cryptosporidiosis.
Antimicrob Agents Chemother
; 66(1): e0156021, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34748385
7.
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Proc Natl Acad Sci U S A
; 116(14): 7015-7020, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30894487
8.
Emerging treatment options for cryptosporidiosis.
Curr Opin Infect Dis
; 34(5): 455-462, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34261904
9.
The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis.
Proc Natl Acad Sci U S A
; 115(42): 10750-10755, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30282735
10.
Characteristics of Mycoplasma genitalium Urogenital Infections in a Diverse Patient Sample from the United States: Results from the Aptima Mycoplasma genitalium Evaluation Study (AMES).
J Clin Microbiol
; 58(7)2020 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32321783
11.
Molecular Testing for Mycoplasma genitalium in the United States: Results from the AMES Prospective Multicenter Clinical Study.
J Clin Microbiol
; 57(11)2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31484702
12.
Herbicidins from Streptomyces sp. CB01388 Showing Anti- Cryptosporidium Activity.
J Nat Prod
; 81(4): 791-797, 2018 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29469575
13.
Conventional strain energies of azetidine and phosphetane: can density functional theory yield reliable results?
J Comput Chem
; 34(7): 558-65, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23108674
14.
Solution structure of CCL21 and identification of a putative CCR7 binding site.
Biochemistry
; 51(3): 733-5, 2012 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22221265
15.
Iron limitation in M. tuberculosis has broad impact on central carbon metabolism.
Commun Biol
; 5(1): 685, 2022 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35810253
16.
Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance.
Commun Biol
; 5(1): 128, 2022 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35149760
17.
Phenotypic screening techniques for Cryptosporidium drug discovery.
Expert Opin Drug Discov
; 16(1): 59-74, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32892652
18.
Repurposing Infectious Disease Hits as Anti-Cryptosporidium Leads.
ACS Infect Dis
; 7(5): 1275-1282, 2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33740373
19.
High-Content Screening for Cryptosporidium Drug Discovery.
Methods Mol Biol
; 2052: 303-317, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31452169
20.
Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase.
Sci Transl Med
; 12(563)2020 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32998973