Detalhe da pesquisa
1.
Cryptosporidium life cycle small molecule probing implicates translational repression and an Apetala 2 transcription factor in macrogamont differentiation.
PLoS Pathog
; 20(4): e1011906, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38669269
2.
Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis.
PLoS Pathog
; 18(2): e1009862, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35134095
3.
Synthesis and structure-activity relationships of aryl fluorosulfate-based inhibitors as novel antitubercular agents.
Bioorg Med Chem Lett
; 98: 129596, 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38142914
4.
Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition.
Bioorg Med Chem Lett
; 90: 129328, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37196868
5.
Repurposing the Kinase Inhibitor Mavelertinib for Giardiasis Therapy.
Antimicrob Agents Chemother
; 66(7): e0001722, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35703552
6.
Pharmacokinetics and Pharmacodynamics of Clofazimine for Treatment of Cryptosporidiosis.
Antimicrob Agents Chemother
; 66(1): e0156021, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34748385
7.
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Proc Natl Acad Sci U S A
; 116(14): 7015-7020, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30894487
8.
Emerging treatment options for cryptosporidiosis.
Curr Opin Infect Dis
; 34(5): 455-462, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34261904
9.
The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis.
Proc Natl Acad Sci U S A
; 115(42): 10750-10755, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30282735
10.
Herbicidins from Streptomyces sp. CB01388 Showing Anti- Cryptosporidium Activity.
J Nat Prod
; 81(4): 791-797, 2018 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29469575
11.
Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance.
Commun Biol
; 5(1): 128, 2022 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35149760
12.
Phenotypic screening techniques for Cryptosporidium drug discovery.
Expert Opin Drug Discov
; 16(1): 59-74, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32892652
13.
Repurposing Infectious Disease Hits as Anti-Cryptosporidium Leads.
ACS Infect Dis
; 7(5): 1275-1282, 2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33740373
14.
High-Content Screening for Cryptosporidium Drug Discovery.
Methods Mol Biol
; 2052: 303-317, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31452169
15.
Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase.
Sci Transl Med
; 12(563)2020 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32998973
16.
A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors.
Nat Commun
; 10(1): 1862, 2019 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31015448
17.
Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis.
Nat Commun
; 10(1): 2816, 2019 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31249291
18.
A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis.
PLoS Negl Trop Dis
; 11(2): e0005373, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28158186
19.
Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.
Int J Parasitol
; 47(12): 753-763, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28899690
20.
A host GPCR signaling network required for the cytolysis of infected cells facilitates release of apicomplexan parasites.
Cell Host Microbe
; 13(1): 15-28, 2013 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23332153